Lege Artis Medicinae

[The role of bone morphogenetic protein in bone healing]

CSÖNGE Lajos1

JANUARY 29, 1992

Lege Artis Medicinae - 1992;2(01)

[The discovery of bone morphogenetic protein (BMP) in the last two decades emphasized the molecular-histogenetic mechanisms of cartilage and bone genesis and healing. Good experimental and clinical results have been obtained with application of new type bone allografts (freeze-dried, antigen extracted, de calcified, chemosterilized) which contain active BMP. Excellent osteoinductive effect and bone healing was detectable by implantation either of these grafts or pure BMP in non-weight bearing defects (bone-cysts, skull defects). Despite of the fact, that a lot of articles have been published on this field internationally, this is the first detailed review in the Hungarian literature which summarizes the most important reported information on the structure, role and clinical application of the bone morphogenetic protein.]

AFFILIATIONS

  1. Petz Aladár Megyei Kórház Pathologiai Osztály Győr

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