Lege Artis Medicinae

[The relationship between premature mortality and marital status in hungary]

HAJDÚ Vargáné Piroska1, BOJÁN Ferenc1

JUNE 29, 1994

Lege Artis Medicinae - 1994;4(06)

[The relationship between mortality and the marital status of Hungarians aged 30–64 was analyzed for the period 1970–1990. The lowest mortality rate was found among married men and women, independent of age. The risk of mortality among unmarried men and women is greater in the age group 30–49 than in the age group 50–59. In both age groups the relative mortality risk of widowed and divorced men is higher than that of the corresponding women. As compared with the married population, the relative mortality risk of men and women who never married is less pronounced, especially in the age group 50– 59. From the late 1970s, the relative mortality risk of divorced men has increased to the greatest extent. As a consequence, in 1980s, the divorced men proved to be the group at greatest risk. ]


  1. Debreceni Orvostudományi Egyetem Társadalomorvostani Intézet Debrecen



Further articles in this publication

Lege Artis Medicinae

[Embryonic diagnostic possibilities prior to implantation]


[A longlasting goal of the medical science has been the prevention of birth defects. Prenatal diagnosis, which is one of the most important subspecialities in modern obstetrics, has developed significantly in the last 10–20 years and has become a powerful tool in fulfiling this aim. The rapid development of the fields of molecular biology, genetics and assisted reproduction has ereated the possibility of introducing the new era of preimplantation genetic diagnosis. Preimplantation genetic diagnosis involves the genetic analyses of the fertilized pre-embryo, without changing its developmental capability or its original characteristics. The most well proven method is the biopsy and rapid genetic analysis by polymerase chain reaction and in situ hybridization of one or two cells removed from the in vitro fertilized pre-embryo. This technique can be used to determine the sex of the pre-embryo or to investigate specific genetic diseases. Numerous other methods have been tried, and the more successful ones are briefly discussed. ]

Lege Artis Medicinae

[Aspects of hormonal therapy in prostate cancer]


[The author describes all of the hormonal therapeutic methods presently applied in Hungary and summarizes the recommended therapies for each stage of the disease. The therapeutic alternatives of three groups of patients are discussed. Evidence in the literature demonstrates the advantages of applying hormonal therapy, in cases of incidental prostate cancer found in tissues obtained by TURP, as opposed to the „wait and see" approach. Emphasis is placed upon the ad vantages of hormonal therapy prior to radical prostatectomy, chief among them being the decrease in volume of the prostate, which simplifies the operation. A promt and total androgenic block is the proper therapy for locally advanced prostate cancer or in metastatic prostate cancer.]

Lege Artis Medicinae

[Treatment of posttransplant polyglobulia with enalapril]


[Posttransplant polyglobulia is not a rare complication following kidney transplantation. Recently in some publications favourable experiences were reported with angiotensin converting enzyme inhibitors in the treatment of polyglobulia. Among 325 patients having kidneys transplanted by authors, polyglobulia was found in 52 patients (16%) after an average of 19,5 months (2,5– 44,2 months) following the operation. In 48 cases, 5 mg enalapril was given orally, independent of the body-weight, for the treatment of polyglobulia. Among them 12 patients – 2 for allergic skin-reactions and 10 for irregular medication – were rejected from the study. During the monthly follow-up of laboratory parameters (Hbg, serum creatinine, serum bilirubin, serum alcalic phosphatase) as well as in the blood pressure (systolic/diastolic) no substantial (significant) difference was found compared to the starting value in the treated 36 patients. The only essential change was the change in the haematocrit level: there was a significant decrease in the haematocrit level after two months from the starting time and this remained so during the investigation. From this study and follow up the authors recommend treating the poly globulia found after the kidney transplantations with enalapril in place of the bilateral nephrectomy used earlier. This treatment is more pleasant for the doctor and the patient.]

Lege Artis Medicinae

[IgE monoclonal gammopathy and amyloidosis]


[ IgE myeloma is a very rare disease with only 38 cases reported in the world literature. The authors describe a case of IgE monoclonal gammopathy leading to primary amyloidosis and death in 5 months. This is the first reported IgE monoclonal gammopathy in Hungary. Diagnosis was based on the immunochemical analysis of the concentrated urine. Histologic analysis relevaled amyloidosis. Despite the fact that IgE myeloma is a rare entity, its clinical presentation is highly variable. This case of IgE myeloma presented itself clinically as amyloidosis. Free light chains could be detected from the patient's serum during the entire course of the clinically active disease. In contrast, heavy chains were not detectable, and therefore immunochemical analysis of the concentrated urine is recommended to help in establishing the diagnosis.]

Lege Artis Medicinae


[The 1st National AIDS Conference; Pharmaceutical production with international cooperation; The turbuhaler in Hungary; Markusovszky Memorial Medal for the President of the Chamber; IV. annual meeting of the Hungarian Psychiatric Society; Astra scholarship for gastroenterologists]

All articles in the issue

Related contents

Hypertension and nephrology

[Gender differences in sport-adaptation of intramural coronary resistance arteries]

TÖRÖK Marianna

[Biomechanical and functional remodeling of coronary resistance arteries in physiological left ventricular hypertrophy has not been analyzed yet, and the possible sex differences are unknown. We aimed to study the biomechanics and function of these arteries during an exercise intervention. Wistar rats were divided into four groups: male and female sedentary controls (MSe and FSe) and male and female animals undergoing a 12-week intensive swim training programme (MEx and FEx). After the training sessions, LV morphology and function were checked by echocardiography, the coronary artery biomechanics and function were examined by pressure arteriography. Elastica remodeling was studied in resorcin-stained histological sections. The female animals had enhanced heart weight/body weight ratio compared to male rats. A similar outer radius and reduced inner radius resulted in an elevated wall-to-lumen ratio in the MEx and FEx animals compared to the sedentary controls. The wall elastic moduli increased in the MEx and FEx rats. The spontaneous tone and TxA2 agonist-induced tone was raised only in ExF animals, whereas the endotheliumdependent relaxation became more effective in ExM rats. Arteries of ExF rats had stronger contraction, whereas arteries of ExM animals had improved dilation. Range of coronary vascular reactivity increased in both exercised male and female rats, but its mechanism was different depending on sex. According to our results the coronary arterioles adapted to an elevated load during long-term exercise and this adaptation depended on sex. The observed sex differences in the biomechanics and function of the coronary resistance arteries of rats may contribute to better understanding of the physiological and pathological function of these arteries in active and retired athletes.]

Lege Artis Medicinae


MÜLLER Veronika, SZABÓ Attila

[Increasing evidence suggests an important role of gender in the incidence, progression and different therapeutic possibilities of several diseases. Recent data demonstrated gender associated differences in the development and progression of chronic renal diseases. Present work reviews sexual dimorphism in different chronic renal diseases, summarizes underlying pathophysiological processes and therapeutic possibilities focusing on the role of gender. New evidences may present the base of gender based therapies in the future.]

Journal of Nursing Theory and Practice

[The importance of serum albumin level in patients with chronic renal disease on maintenance dialysis]

TÓTH Csitkovicsné Tünde, SZAKÁCS Gyuláné, KULCSÁR Imre

[The aim of the study: Evaluation of changes in serum albumin levels and their effects on mortality in chronic haemodialyzed (HD) population. Material and Methods: We analysed the serum albumin values and survival in 253 HD patients, in a retrospective observational study. Data were analyzed using Spearman-correlation, Cox-modell, endpoint analysis and Kaplan-meier analysis. Results: We did not find any significant correlation between serum albumin levels and gender or basic diseases, but the median serum albumin level was lower in patients with ages 65 years or older than in younger ones, and had decreased until observational period (5.4±3.0 years). Lower the serum albumin level the risk of mortality was higher (if the serum albumin level was <35 g/L versus >40 g/L), the HR was 5.69. Conclusions: The serum albumin level is a main indicator of the nutrition in dialyzed patients, but the target level would be different in older and younger patients. The serious malnutrition (lower serum albumin level) increases the risk of mortality in haemodialyzed patients.]

Lege Artis Medicinae

[Trends of mortality amenable to health care in Hungary and in the Central Region, 1996-2006]

NAGY Csilla, JUHÁSZ Attila, PÁLDY Anna

[INTRODUCTION - Despite of the decreasing trend of amenable mortality it is a significant contributor to social and economic loss due to premature death. This paper assesses the trends of amenable mortality over time, its contribution to the years of potential life lost (YPLL), furthermore reveals the spatial inequalities of the amenable mortality in the central region in relation to socioeconomic status and number of the inhabitants of municipalities. METHODS - This study describes the trend of the years of potential life lost due to amenable mortality during the period 1996-2006 in Hungary, in Pest county and in Budapest. The spatial epidemiological analysis of the amenable mortality was carried out by using smoothed indirectly standardised mortality ratio calculated by full hierarchical Bayesian methods at municipality level. The association between the spatial distribution of amenable mortality and socio-economic status was assessed by using a “Deprivation Index” elaborated by the authors. RESULTS - The years of potential life lost of males were 7207 (per 100 000) and respectively for females these value was 3870 (per 100 000) in Hungary in 2006. The amenable mortality is a significant contributor to years of potential life lost despite its decreasing trend. The amenable mortality accounted for approximately one third of the males’ and the females’ years of potential life lost. The risk of amenable mortality is higher in the less populated areas and the less-favoured socioeconomic situation coexists with high mortality risk. CONCLUSION - Approximately in average 32 000 persons died due to amenable mortality per year during the investigation period in Hungary. The results of the study provide essential information to the local policy-makers, and managing health professionals. The results can be used principally to inform planning healthcare development programs.]

Clinical Neuroscience

[Vasoreactivity changes of healthy volunteers investigated by transcranial doppler]


[Transcranial Doppler (TCD) was used to measure the effect of 1 g acetazolamide (Diamox, Lederle) on blood flow velocity in the middle cerebral artery of 50 healthy volunteers (aged 20-70 years). Parameters of blood flow, blood pressure, heart rate and blood gas values were determined before and after intravenous administration of Diamox. The reserve capacity was expressed as a percentage change of baseline values. The acetazolamide did not result in significant blood pressure and blood gas changes. The mean velocity of blood flow before Diamox administration was 59.8+14.4 cm/s. The velocity of flow significantly increased after acetazolamide, peaking after 10 minutes. The extent of reserve capacity was the greatest in the age group of 31-40 years and the smallest in the 61-70 years group. The reaction was longer lasting in age groups over 50 years. Significantly higher flow parameters and greater reserve capacity was found in women than in men at each measuring time point. The reserve capacity depended on age and gender.]