Lege Artis Medicinae

[The formation and history of public hospitals – Szent László Hospital]

LUGOSI Lugo László, ZÖLDI Anna

OCTOBER 07, 2024

Lege Artis Medicinae - 2024;34(9)

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Further articles in this publication

Lege Artis Medicinae

[Money or life?! Or, money talks… – Thoughts on financing of Hungarian health care in connection with Éva Orosz’s study]

KAPÓCS Gábor

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Lege Artis Medicinae

[Dear Readers!]

BENCZÚR Béla

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Lege Artis Medicinae

[Continuous glusose monitoring in application of insulin glargine plus lixisenatide fixed ratio combination ]

HERMÁNYI Zsolt, JANKOVEC Zdenek , MAULE Petr , TAYBANI Zoltán Jamal, VESELÁ Alica , BONNEMAIRE Mireille , FÜLÖP Rita

[The effectiveness of the fixed-ratio combination of insulin glargine and lixisenatide (iGlarLixi) has been confirmed by several clinical trials in people with type 2 diabetes (T2DM). The aim of this study was to demonstrate the effectiveness of iGlarLixi treatment in improvement glycemic control in participants who were inadequately controlled on basal insulin using continuous glucose monitoring (CGM) data.

The primary endpoint of this 18-week, single-arm, open-label, phase 4 clinical trial was the change of blood glucose level time in range (TIR). The inclu­sion criteria were at least 3-year T2DM and 6-month treatment with basal insulin, HbA1c level ≥7.5% and ≤10% and fasting blood glucose level ≤7.8 mmol/l. CGM data recording was performed before the switch to iGlarLixi and at the 18th week. Dose titration of iGlarLixi was based on self-monitoring of blood glucose levels.

Overall 51 participants were treated with iGlarLixi and 34 participants had baseline and end-of-study CGM recordings (“per-protocol population”). The per-protocol population’s mean (SD) age was 66.4 (7.01) years and they have had T2DM for 16.6 (9.06) years at inclusion. The percentage of TIR increased from 71.8% (18.08) to 78.3% (12.36) (p=0.066), while the time above range (TAR) decreased significantly from 24.0% (18.96) to 9.9% (9.85; p<0.001). The percentage of time-below-range (TBR) increased from 4.2% (7.23) to 11.8% (13.48; p<0.001). The HbA1c level decreased from 8.4% (0.63) to 7.1% (0.91), and the fasting blood glucose levels also decreased.

This study confirmed the effectiveness of iGlarLixi using CGM data and provided numerous learnings for designing future CGM studies.]

Lege Artis Medicinae

[VI. Szekszárdi Hypertonia Napok]

BENCZÚR Béla

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Lege Artis Medicinae

[The possible role of being  a near-peer school health  educator in medical education    ]

ÁRVA Dorottya, CSEH Annamária, JENEY Anna, DUNAI Diána, MAJOR Dávid, ZÖRGÔ Szilvia

[Lack of skills, commitment, and physicians’ poor health beha­vior may hinder lifestyle counseling in medical practice, but these barriers can be mitigated by training. We aimed to explore how school-based peer health education during training may improve medical education. We examined among educators of the Ba­las­sagyarmat Health Education Program (BEP) what kind of experiences they gained useful for lifestyle counseling, how committed they became to health edu­cation, and whether their health behavior changed. 

Semi-structured interviews were conducted with medical student near-peer educators of BEP (n = 9) who had mastered all topics of the program. Our data were subjected to qualitative content analysis. Our deductive codes were defined by the research questions, and responses to these were inductively coded and aggregated along the questions. 

Among the skills useful for lifestyle counseling, the participants experienced improvement in patient education, motivation, and partnership-building. They became more committed and after the program voluntarily and successfully carried out health education in their communities and among patients. They reported more conscious nutrition, alcohol consumption, and increased physical activity as changes in their own behavior. 

The school-based health education program helped medical student near-peer educators improve medical communication skills and commitment to health education, and spurred positive health behavior change; thus, we recommend considering its integration into medical education. 

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[Pain intensity is the most frequently assessed health domain in clinical studies among patients with low-back pain. Visual analogue scale (VAS) and Numeric rating scale (NRS) have been the mostly used measurement tools for pain intensity. We proposed to correlate these instruments to a generic health-related quality of life measurement tool in order to show the scale with superior clinical relevance.

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[The independent living of older people, who form an increasing proportion of society, is fundamentally determined by falls and the fear of falling. Fear of falling becomes pathological when loss of self-confidence and experience of fear of falling become persistent. Consequently, physical activity of older people becomes also limited, which compromises their future functional abilities and increases the risk of institutionalisation. This narrative review discusses the terminology used in the literature, the prevalence of fear of falling, and the methods used to evaluate it. It also outlines how it can be prevented and how it can be reduced (or even eliminated) based on current research.]

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Lege Artis Medicinae

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