Lege Artis Medicinae

[The Black Angel]

FRENKL Róbert

FEBRUARY 20, 2001

Lege Artis Medicinae - 2001;11(02)

COMMENTS

0 comments

Further articles in this publication

Lege Artis Medicinae

[The role of steroid hormones in the protection against oxidative stress]

BÉKÉSI Gábor, FEHÉR János

[The incidence of vascular diseases increases in postmenopausal women. This negative trend seems to be controllable favourably by hormone replacement therapy (HRT). Based on the free radical mediated mechanism of atherogenesis the authors try to find the reasons for these observations on the basis of their and others’ data. They consider the increase of activity and amount of neutrophil enzyme myeloperoxydase by certain steroid particulars one of the most important elements of the vasoprotective effect of HRT. This increase diminishes the production of superoxide anion by the inhibition of the NADPH-oxidase enzyme. The observation proved firstly by the authors, that the plasma levels of myeloperoxydase - and so the ability for the inhibition of superoxide anion production by neutrophils - decreases in elderly people, might explain the higher incidence of some free radical mediated illnesses in the elderly. The authors also give a short review of antioxidant effects of steroids in general.]

Lege Artis Medicinae

[The importance of vitrectomy in the management of diabetic retinopathy in proliferative stage]

BERECZKI Árpád

[Vitrectomy is a closed microsurgical technique, by which intraocular tissue, blood and foreign bodies can be removed through a small incision in the pars plana with an automated suction-cutting device (vitrectom), while maintaining normal or slightly elevated intraocular pressure. This technique requires many accessory instruments (microscope, endoillumination, intraocular instruments, endolaser). The main application of vitrectomy is the treatment of severe complications in diabetes mellitus: diabetic retinopathy in the proliferative stage. Vitrectomy is indicated in diabetic retinopathy for the removal of intraocular bleeding and for the treatment of complications of diabetic proliferative vitreoretinopathy (recurring bleeding, tractional and rhegmatogenous retinal detachment). In the case of intraocular bleeding, early vitrectomy is better than delayed, providing good visus (V: 0,5) in 25% of all patients (based on literature data). In retinal detachment cases of tractional origin, surgery provides satisfactory visus for self-care in 2/3rd of all patients.]

Lege Artis Medicinae

[Alphabetic index 1991-2000]

Lege Artis Medicinae

[„There should be someone to hold the hand of the dying!” Deep interviews on the difficulties of caring for the dying]

BOGNÁR Tamás, KOLOSAI Nedda, HEGEDÛS Katalin, PILLING János

Lege Artis Medicinae

[Gastrointestinal stromal tumor]

GONDA Gábor

[Gastrointestinal stromal tumors were subject of much controversy in the last decades. This type of tumors was delineated from the leiomyoma - leiomyosarcoma group. GISTs show variable histological picture, moreover, they are capable of dual (neurogen and myogen) differentiation as it is proved by immunohistochemical and ultrastructural studies. These tumors have relatively good prognosis, only 10-30% of them is malignant, although it is difficult to predict their behaviour in a given case. The most reliable signs of malignancy - cytological pleoimorphism, high mitotic activity, proliferation index above 10 %, and aneuploid DNA content - are generally accepted. The treatment of choice is excision, but not enucleation. Radical surgery is not necessary, since lymph node metastasis is exceptionally rare. Further investigations revealed electronmicroscopical and immunohistochemical (CD 34, CD 117) similarities of tumor cells and interstitial cells of Cajal (ICC) located in the wall of the bowel. The results of these investigations led to the theory that cells of GIST and ICCs are of the same stem cell origin. Molecular genetic studies are also of great help in the differential diagnosis and in predicting the prognosis of GISTs. Mutations in the c-kit gene can not be detected in leiomyomas, so they are thougt to be specific for GISTs. Mutation of exon 11. of chromosome 4. is observed only in malignant GISTs.]

All articles in the issue

Related contents

Lege Artis Medicinae

[Saint László, protector against the plague]

KERNY Terézia

[The Hungarian cult of the plague, or in the vernacular the cult of the saints (Sebestyén, Rozália, Rókus) who protect against the black death, glandular death, and death by pestilence (1), has been most thoroughly described by Sándor Bálint. His research was continued by Zoltán Szilárdfy, who compiled an iconography of the anti-plague images of the Virgin Mary, embedded in a broad historical and ethnographic context (2).]

Lege Artis Medicinae

[“Let’s Open the Window so that the Angel will Fly in to Us!” A Discussion with Ádám Fellegi]

GYIMESI Ágnes Andrea

Lege Artis Medicinae

[Magic against the "black death"?]

KOVÁCS Zoltán

[Among the epidemic diseases that have terrified and frightened mankind for centuries, the plague, also known as the "black death", is the most common. Even today, many of us shudder at the mere mention of its name, although fortunately we have little personal experience of the disease. What was the constant experience of successive generations in the Middle Ages is almost unimaginable to 20th century man: an epidemic that regularly appeared and claimed huge victims. In the old chronicles, we often find descriptions of plague epidemics which, although they tend to exaggerate the number of victims, give a vivid picture of the shock of the devastating power of the disease in the minds of the people of the time. ]

Lege Artis Medicinae

[Black Magic, or Resurrecting the Dead Mother ]

GEREVICH József

Lege Artis Medicinae

[Stories of the Black Square ]

RÁCZ József