Lege Artis Medicinae

[The advantages of the combination of amlodipine and atorvastatin and the experiences with the therapy]

KÓRÓDI Tünde

SEPTEMBER 21, 2014

Lege Artis Medicinae - 2014;24(08-09)

[Hypertension and hyperlipidaemia are two major risk factors, as well as a single factor, but together are even more responsible for the cardiovascular death, which still isn’t reduced significantly in Hungary. About 2.5 million people suffer from hypertension in Hungary, and almost half of them do not reach the target level, and two-thirds of them have hyperlipidaemia as well. These risk factors are associated with other diseases. Obviously these illnesses can not be treated only with one drug. The European guidelines of the treatment of hypertension (ESH/ESC 2013) emphasise the importance of priorital of two-drug combinations, there is an evidence for the fix combinations of patients with major multiple risk factors in the beginning of the therapy. We used the combination of amlodipine/ atorvastatin in the treatment of hypertension during a three month period. The level of the blood pressure decreased of 18/11 mmHg, the cholesterin and the triglicerid values decreased 0.56 and 0.7 mmol/l. The patients got advices for the right lifestyle as well. In conclusion it can found, that the fix-drug combinations can improve the adherence, and they can help in the rigorous control of hypertension to prevent and treat the car­diovascular diseases.]

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