Lege Artis Medicinae

[MENOPAUSE AND CARDIOVASCULAR RISK]

MASSZI Gabriella

SEPTEMBER 15, 2006

Lege Artis Medicinae - 2006;16(08-09)

[The physiological changes of menopause are associated with an increase in cardiovascular risk. Cardiovascular diseases lead mortality statistics also in women. Several physiological effects of oestrogen are thought to be protective for the circulatory system. The reasonable idea of hormone replacement therapy, however, has not met the expectations. This article reviews the relevant studies and discusses the possible causes of failure. The second part focuses on the issue of prevention. The Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women, a recommendation developed in the US, is delineated. Hungarian data are provided based on results of the Menokard programme. The paper gives an overview of hormone replacement therapy and cardiovascular prevention in postmenopausal women.]

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