Lege Artis Medicinae

[Jelentés a 2013. évi magyarországi gasztroenterológiai endoszkópos tevékenységről]

NAGY György, OROSZ Péter

SEPTEMBER 21, 2014

Lege Artis Medicinae - 2014;24(08-09)

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[Polyneuropathy as a first sign of microscopic polyangiitis]

ZÖLD Éva, HORVÁTH Ildikó Fanny, TARJÁN Péter, BARTA Zsolt, ZEHER Margit

[INTRODUCTION - Microscopic polyangiitis (MPA) is a systemic autoimmun disease characterized by necrotizing small vasculitis. MPA belongs to the ANCA-associated vasculitides. The disease can affect many of the body’s organ systems. Major organs involved are kidneys, skin, peripheral nerves and lungs. In addition, generalized symptoms such as fever and weight loss are very common. CASE REPORT - In January 2013 a 56-year old woman presented with weight loss, lower leg numbness, walking difficulty and petechiae on the lower legs. One month later, laboratory examinations showed progressive kidney dysfunction, anemia, hypersedimentation and elevated C reactive protein level, but further tests and investigations for potential bacterial infection and tumors were all negative. In sum, clinical signs and symptoms suggested systemic vasculitis, which was proved by the kidney biopsy and ENG examination. From these findings, microscopic polyangiitis was diagnosed with polyneuropathy and glomerulonephritis. The patient was a Hepatitis B (HBV) virus carrier, which can be provoking factor for vasculitis. Corticosteroid and six treatment cycles of intravenous pulse cyclophosphamide were performed for induction of remission. After treatment her symptoms improved and kidney function was normalized. Antiviral treatment was started because of HBV reactivation in October 2013. As a new manifestation of MPA, pulmonary symptoms were appeared in November 2013 and the patient was treated with synchronization of plasmapheresis and pulse cyclophosphamide with good clinical effectivity. Now, she is treated with methotrexate as immunosuppressive treatment and control examinations indicate the remission of the disease with proper renal function. CONCLUSION - We draw attention to a rare case of vasculitis and underline the importance of both the early diagnosis and the early and effective immunosuppressive therapy. Peripheral neuropathy may occur as a result of having systemic vasculitis. Nevertheless, the exploration and elimination of provoking factors are also must be part of the management and the regular follow-up is essential to recognize the disease relapses, thus avoid permanent organ damage.]

Lege Artis Medicinae

[Anna Tompa MD: Globalization and Health ]

BALÁZS Péter

Lege Artis Medicinae

[Hungarian health care professionals’ attitudes and habits regarding blood donation in different professional groups]

RAJKI Veronika, HIRDI Henriett Éva, BALOGH Zoltán, MÉSZÁROS Judit

[INTRODUCTION - We carried out a survey in Hungary among health care workers, we surveyed their habits in blood donation and their knowledge about the blood donation. METHODS - A cross-sectional study happened between 15th July and 15th Sep-tember in 2012 among the Adult nursing care-, Emergency care-, Surgical care-, and Maternity care professional groups, with convenience sampling statistical method (n=312). The data collection happened with a web-based, anonymous, self-administered questionnaire. For the edited electronic questionnaire we used some question from the “Eurobarometer 41.0 (1995): Europeans and the blood” survey. We analyzed the collected data with IBM SPSS Statistics 20 software and Kingsoft Office Spreadsheet (2012) program, using by descriptive statistical methods. RESULTS - The survey has occured with the participation of 312 health care workers. The blood donation activity of the health care workers in every professional groups was higher than the national average in a EU survey stated in 2009. 61.86% of the health care professionals give blood at least twice a year at different locations. The most common causes of the non-appearance from blood donation were the “other reasons”, “earlier forbidden from blood donation” and “lack of time”. We found differences in their view in each groups about refusing/authorizing blood transfusion, but these have no great importance. CONCLUSION - Regarding to our results we recommend to open the eyes to the need for common, aligned collaboration, and to the modifying the current competencies, to the betterment of the opportunities for further trainings in order to further increase of blood donation habits and attitudes. ]

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[Arthur Görgei’s Head Wound ]

ÓCSAI Antal

Lege Artis Medicinae

[Fulvestrant and long progression free survival: a patient with metastatic breast cancer]

BÁNHEGYI Róbert János, LACZÓ Ibolya, FÜLÖP Ferenc, MELLÁR Erzsébet, CSIFFÁRI Margit, PIKÓ Béla

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