[Precision medicine proposes the personalization of health services in order to make the best individual decisions about the interventions and treatments for the patient. Molecular genetic diagnostic tests help to select the appropriate therapy, so-called targeted therapy. In the case of extensive lung cancer with EGFR mutation, EGFR tyrosine kinase inhibitors are immediately applicable; they are very effective and can reach long-term remission of the disease. However, resistance mutation can develop during the treatment, which causes the progression of the disease; therefore change of therapy is needed. In our case, we show the possibility of targeted treatment beyond the progression, emphasizing the importance of detecting resistance mutation. ]

[Combining oncology with philosophy, as seemingly two different disciplines, is an exciting task but the question arises as to why this is necessary. For thousands of years philosophers have been trying to find answers to the basic questions of being-existence, reality, death, morality but from the twentieth century we see less and less the daily significance of these. Are not “questions of existence” important or are they no longer relevant? We would like to believe they are not but there are situations where suddenly our existence is threatened and all our already gained life experiences are proved to be a failure…]

[The Hungarian literature has quite ignored so far Noyes & Clancy’s Role Theory approach of dying. I present the outline and a critique of this conception, then lay the foundations of a reformed concept of the dying role. For the optimal and desired dying role is not one of peripherising and objectifying, rather one of placing the dying in the centre of the system of relations and roles radically restructuring under the influence of such role. The personality of the dying remains a true value in this central position. The reintegration of the dying can begin parallel to her disintegration by the progressive loss of her normal social roles (‘the loneliness of the dying’). Death can thus transform into a social phenomenon. I illustrate the argumentation on the central dying role with a case study using the method of a heterophenomenological, second-person character. By promoting the central and autonomous dying role, i.e. by the development of the necessary social role competences, or at least by publicising the thanatological knowledge, death can turn from an avoided, socially disintegrative taboo into a phenomenon that can strengthen the community even after the dying departed.]

[Ocular surface disease is a frequently seen condition in the elderly in the general po-pulation. In glaucoma patients the glaucoma-therapy related ocular surface disease is a particularly serious and common condition with complex pathogenenesis. Pre-servatives, most commonly benzalkonium chloride, employed in intraocular pressure lowering eye drops frequently cause or worsen ocular surface disease in glaucoma. The symptoms frequently undermine both the adherence to the prescribed intraocular pressure lowering drops and the vision related quality of life. Therefore the success of long-term glaucoma care in glaucoma-therapy related ocular surface disease is reduced. The current article summarizes the main pathogenetic aspects of glaucoma-therapy related ocular surface disease, and presents how to eliminate the main causative factor and normalize the ocular surface by using completely preservative free topical medication in glaucoma. ]