Lege Artis Medicinae

[Explorative statistical analysis of numerous blood tests’ metabolic panel with rank-correlation ]

BRYS Zoltán1, NAGY Erzsébet2, MAGYAR Gábor1, MOLNÁR D. László3, KIS János Tibor4

DECEMBER 10, 2019

Lege Artis Medicinae - 2019;29(12)

DOI: https://doi.org/10.33616/lam.29.057

[INTRODUCTION AND AIM - During rou­tine blood panel testing, large amounts of bio­medical data are collected in Hungary and in all over the world. The aim of our - ethically approved - exploratory medical data analysis was to examine whether the analysis of correlations among several variables in a real-life, non-random blood panel data leads to meaningful results. DATA AND METHODS - In a retrospective study 2,292,199 anonymous routine blood panel data points were analyzed. Rank correlation was used between variables with more than 10,000 data points and strong (|ϱ|>0.5, p<0.001) relationships were visualized and interpreted. RESULTS - Similar laboratory values, effects of diseases affecting the same organ, as well as well-known medical interrelationships were shown between the examined laboratory parameter-pairs. DISCUSSION - Our exploratory data analysis shows that despite the non-random nature of the big blood panel sample, well-known medical correlations were very well detectable. Based on the results further re­search - with the inclusion of additional variables - seems reasonable and meaningful with due caution.]

AFFILIATIONS

  1. Budapesti Mûszaki és Gazdaságtudományi Egyetem, Villamosmérnöki és Informatikai Kar, Távközlési és Médiainformatikai Tanszék
  2. Betegellátó Irgalmasrend, Budai Irgalmasrendi Kórház, Központi Laboratórium
  3. Állatorvostudományi Egyetem, Haszonállat-gyógyászati Tanszék és Klinika
  4. Betegellátó Irgalmasrend, Budai Irgalmasrendi Kórház, Belgyógyászati Centrum

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Lege Artis Medicinae

[Comment to the article titled “Exploratory study of outcomes of blood sample mass examinations by rank correlations”]

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[The author’s response to the comment on “Exploratory study of outcomes of blood sample mass examinations by rank correlations”]

Clinical Neuroscience

Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

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