Lege Artis Medicinae

[“Dog’s cosmic barking” – Zsuzsanna Nemesi Nagy ]

ABODY Rita

DECEMBER 21, 2020

Lege Artis Medicinae - 2020;30(12)

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Lege Artis Medicinae

[Risk of nonsteroidal antiinflammatory drugs. Focus on aceclofenac]

FARSANG Csaba

[Nonsteroidal antiinflammatory drugs (NSAIDs) are among the most frequently used pharmaceuticals. Nevertheless, a number of studies emphasized that NSAIDs were damaging not only the gastrointestinal (GI), but also the cardiovascular (CV) system, could increase the blood pressure, the frequency of coronary events (angina, myocardial infarction) and stroke incidence, as well as they might deterio­rate renal functions. The National Institute for Health and Care Excellence (NICE) did not find evidence that administering NSAIDs could increase the risk of developing COVID-19 or worsened the condition of COVID-19 patients. However, unwanted effects of specific drugs differ substantially in their occurrence and seriousness as well. It seemed to be for a long time that the NSAIDs provoked higher GI-risk was closely related to the COX1/COX2 selectivity, like the cardiovascular (CV) risk to the COX2/COX1 selectivity, however, the recent data did not prove it clearly. Based on the available literature while pondering the gastrointestinal and cardiovascular adverse events, among all NSAIDs the aceclofenac profile seemed to be the most favourable.]

Lege Artis Medicinae

[The LAM’s 30 years]

FARSANG Csaba

Lege Artis Medicinae

[LAM 30: 1990–2020. Facing the mirror: Three decades of LAM, the Hungarian medicine and health care system]

KAPÓCS Gábor

Lege Artis Medicinae

[History of vaccine production in Hungary ]

ÓCSAI Lajos

[This study presents the complete history of the Hungarian vaccine production, partly in association with the process of fighting vaccine-preventable infectious diseases, and underlines the fact that every government actively contributed to the age-adjusted mandatory vaccination schedule of the past 140 years. It demonstrates the various achievements from the smallpox lymph production through the launch of diphtheria serum production at Phylaxia and the establishment of the National Public Health Institute (OKI) with its vaccine production and the later institutional transformation of OKI into Humán as economic corporation to its closure. Among all OKI’s vaccine production activities, this study focuses on the production of influenza vaccines, due to its international importance in the 1960s and 1970s. The vaccine production against diphtheria tetanus and pertussis stands out from Humán’s activities, and the tetanus component of this vaccine is still used in the products of a multinational vaccine manufacturer. ]

Lege Artis Medicinae

[30 year history of surgery and the surgeon’s future ]

KUPCSULIK Péter

[During the past 3 decades, laparoscopic surgery has launched a revolution in operative medicine. The German gynaecologist Kurt Semm transformed the diagnostic laparoscopy for therapeutic procedure, as he performed the first laparoscopic ap­pen­dectomy. The surgeon Erich Mühe contributed with laparoscopic cholecystectomy to the set of surgical instruments. All over the world, a wide spectrum of laparoscopic procedures has been app­lied. Several laparoscopic procedures are now preferred over open approaches. Morbid obesity is associated with significant comorbidity and mortality. In­suffi­ciency of dietary measures lead to development of surgical interventions that resulted in unexpected excellent outcomes. “Metabolic surgery” was born. New methods and rising market of socio-medical requirements inspired progress in plastic surgery. Thanks to innovations in technology, reconstructive breast surgery has opened new ways. In the 1990s the prototype of “mas­ter–slave” robot controlled by a surgeon was constructed. Future of robotic surgery depends on cost reduc­tion, development of new technologies and creating the best applications. Coo­pe­ra­tion with partner medical specialities is essential for further development in surgery. Despite of obvious impact of new technologies the surgeon's way of thinking, personal qualities decision-making and professional knowledge remain cru­cial for further evolution. ]

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[Normal values of total body mineral content in the Hungarian female population]

LÁNYI Éva

[BEVEZETÉS - A magyar nők egész test ásványianyagtartalmának populációs normálértékeit kívántuk meghatározni. VIZSGÁLT SZEMÉLYEK ÉS MÓDSZEREK - Hétszáz egészséges, különböző életkorú nőt vizsgáltunk kettős energiájú röntgenfoton-abszorpciometriával. A vizsgálat során meghatároztuk az egész test tömegét (TBM), ásványianyag-tartalmát (TBMC), lágyrész-tartalmát (TSTM), zsírtartalmát (fat), az ásványi anyag és a zsírmentes szövet hányadosát (TBMC/LBM), valamint a különböző testtájak (fej, törzs, jobb és bal kar, lábak) ásványianyag- és lágyrész-tartalmát, továbbá a testsúlyból és a testmagasságból számolt testtömegindexet (BMI). EREDMÉNYEK - A magyar nők egész test ásványianyagtartalma a 20-30 év közötti korcsoportban a legmagasabb. Ez nem változik lényegesen a 46-50 éves korcsoportig, ahol jelentősebb csökkenés következik be. Az ásványianyagtartalom további nagyobb mérséklődése az 56-60 éves korcsoportban észlelhető, majd 60 éves kortól a csökkenés fokozatosan, nagyobb lépcsők nélkül következik be. Az egész test lágyrész-tartalma ellentétes változást mutat, mint az egész test ásványianyag-tartalma. A lágyrész-tartalom az életkorral párhuzamosan egyre nő, de ez a növekedés az egész test zsírtartalmának emelkedéséből származik. A testtájak ásványianyag-tartalmát összehasonlítva a végtagok ásványianyag-tartalmának fokozatos csökkenése észlelhető. Megfigyelhető a két kar közötti különbség, ez a domináns jobbkezességből adódik. A törzs ásványianyag-tartalma az életkor előrehaladtával folyamatosan csökken. KÖVETKEZTETÉSEK - Az egész test ásványianyagtartalmának vizsgálata egyre jelentősebb szerephez jut a szekunder osteoporosisok vizsgálatánál, így a populációs normálértékek meghatározásának különösen nagy a jelentősége.]

Journal of Nursing Theory and Practice

[Value research of students in the patient care sector. Research carried out in a vocational secondary school]

KOVÁCSNÉ MELHER Marianna

[Aim of the study: Mapping out the value system, the professional motivation and the socio-cultural background of care provider students at the Zsuzsanna Kossuth Vocational Secondary School Sample and methods: Descriptive type research, number of elements 169 (n=169). The data was synthesized with Microsoft Office Excel 2007. Results: Taking into consideration the influence of the parents’ educational and professional background it can be stated that the parents’s influence gains control of their children’s school choice. In every analyzed group students are backed by strong family support. Regarding their career choice most students were motivated by the desire to help people. Graduate students demonstrate a more consistent career choice than younger students. The most important values of the care provider career proved to be: professional knowledge, know-how, responsibility and precision. An increase in career values related to age has not been demonstrated. Conclusions: It is very important to know the students’s value system because the values gained in the family and at school play a determining role in the care providers’s job. ]

Lege Artis Medicinae

[Deadly Caress, or the Apotheosis of Cosmic Pain ]

GEREVICH József