Lege Artis Medicinae

[Diagnostic possibilities in giardiasis]

DÖNGÖLŐ László1, NEMESÁNSZKY Elemér1, NEUMARK Tamás2

MAY 27, 1992

Lege Artis Medicinae - 1992;2(05)

[Giardia lamblia is the most commonly found pathogenic parasite in the Western World. Recently cysts of Giardia lamblia were isolated from drinking water in Hungary. Giardiasis is an infection that is often not promptly suspected and diagnosed because of the greatly variable expression of the disease. The spectrum of presentation is broad: there are asymptomatic individuals and patients showing gastroenteritis or hepato-biliary syndrome as well as gastritis-duodenitis syndrome. Giardia alters the absorbtive function of the villus tip in the upper small bowel resulting in noninflamatory diarrheal illness. The traditional microscopic examination of stool samples yields low diagnostic sensivity compared with light microscopy of duodenal aspirate, endoscopic brush cytology, mucosal inprint or biopsy. Sensitive immunological detection methods like immunodiffusion indirect fluorescent antibody and ELISA tests might greatly enhance the possibility of detec ting anti-Giardia antibodies. Most of these serodiagnostic assays are not available for routine diagnostic purposes. Our data suggest that the light microscopic examination of duodenal aspirate and endoscopic brush cytology together are fast, cheap and reliable methods for detecting Giardia trophozoites. When these methods fail to reveal Giardia infection electronmicroscopy could help reaching the correct diagnosis. ]

AFFILIATIONS

  1. II. Belosztály Országos Reuma és Fizioterápiás Intézet
  2. Kórbonctani Osztály Országos Reuma és Fizioterápiás Intézet

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