Lege Artis Medicinae

[Correspondence]

SZOMBATI István1, MANNINGER Jenő2, KAZÁR György2, HARMAT Pál, MÁRTON Éva3, KRASZNAI Géza4

APRIL 29, 1992

Lege Artis Medicinae - 1992;2(04)

[Includes the following letters : Little Hungarian point system; ...and the injured?; Abuse of psychosomatics the organic dimension of psychiatry; Psychogenic horsekick; ]

AFFILIATIONS

  1. Országos Reuma és Fizioterápiás Intézet, Budapest
  2. Országos Traumatológiai Intézet
  3. III. Pszichiátriai és Rehabilitációs Osztály
  4. Kórbonctani és Kórszövettani Osztály

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[Malnutrition syndrome in childhood part I.]

BAKSAI László, PHILIP W. H. Eskes

[Malnutrition is a chrocic nutritional disorder resulting from insufficient intake of caloric energy and/or some the fundamental nutrients. Since it is the most common public health problem in the world it has a great impact on pediatric morbidity and mortality. The etiology is extremely complex. When one considers the less severe symptoms and signs caused by vitamin-, mineral-, and trace element deficiencies, it is apparent that not only children living in underprivileged countries are affected. In the course of making the diagnosis an assessment of the nutritional status should also be made, especially considering the above-mentioned marginal nutritional deficiencies. The most common manifestation of nutritional disorders is anemia, which is mostly caused by lack of iron, vitamin B12, folic acid and can be complicated by infections. Nutritional requirements can be affected by several drugs. That is why this medication-nutrition interaction has to be kept in mind during treatment. The interaction of malnutrition and infection is very important, primarily for three reasons: mechanisms by which infection complicates the metabolic and nutritional status of the host; importance of suboptimal nutritional status on susceptibility and severity of intercurrent infections; clinical and therapeutic implication of these interactions. ]

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[The bleeding time]

BODA Zoltán

[The bleeding time is considered to be the best screening test for the detection of disorders of primary haemostasis. Despite a large number of bleeding time tests, the exact pathophysiological background of the prolonged bleeding time is unknown. The significance of the cellular (platelet) von Willebrand protein is emphasized. A sensitive method (Ivy) and standardized devices (Simplate) are suggested. Examination of the bleeding time in cases of von Willebrand disease and congenital or acquired thrombocytopathy is essential. Specific recommendations regarding the rational use of the bleeding time (diagnostic algorythm) are presented. ]

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[Clinical importance of pharmacogenetic investigation]

VAS Ádám, RÓNA Kálmán, GACHÁLYI Béla , SZABÓ Ildikó

[This is a brief review on the most important monogenically determined metabolic polymorphisms, their biochemical background and clinical significance. Relevant data from literature are also featured. The authors review data on possible connections between metabolic polymorphism and the risk of certain diseases.]

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[P300 wave evoked by visual and acustic stimuli in parkinsonian patients with or without dementia]

MOGYORÓS Ilona, SZOMBATHELYI Éva

[Authors analysed the relationship between cognitive function disturbance observed in patients with Parkinson's disease and clinical features of the disease. Relationship between the latency prolongation of the P 300 wave and the duration of substitution therapy, clinical form and severity of the disease (the Hoehn-Yahr stage) was examined. 75 randomly selected young patients with Parkinson's disease were divided in to two groups: one with and the other without dementia as determined by the Wechsler. Hunt and Mini Mental State tests. The latency of the P 300 wave using visual and acoustic stimuli was determinated. Significant prolongation of the latency of P 300 wave evoked both by visual and acoustic target stimuli was found in parkinsonian patients with dementia. Patients with dementia have longer duration of disease and substitution therapy. The akinetic-rigid form of the disease was more frequent in this group as well. A significant part of younger patients are chacarterised not only with motor but with cognitive function disturbance, too. Determination of the latency of P 300 wave helps to select these patients and to choose the adequat therapy. ]

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[Monitoring the immunophenotype of mononuclear cells in the cerebrospinal fluid acute lymphoid leukemia patients]

BABOSA Mária

[Cerebrospinal fluid and blood samples were drawn at scheduled intervals from recently diagnosed or recurrent acut lymphoid leukaemia patients undergoing combined cytostatic therapy. The immunophenotype of mononuclear cells, separated from the samples, was determined and compared. It was found that the number of non-pathological mononuclear cells increased from time to time during the intense treatment period of ALL patients with high malignancy or recur rence and that their phenotype was similar to the actual surface markers of peripheral lymphocytes. According to findings in the literature based on monitoring other parameters, this phenomenon may be due to the increased permeability of the blood brain barrier, injured by intense chemotherapy and radiotherapy, or to reactive cell proliferation. ]

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[Schizotypal traits and verbal creativity]

FEJES Nikolett Éva, RÓZSA Sándor, MUST Anita

[Introduction - The relationship of schizophrenia and its milder, subclinical forms, with creativity has been in the centre of theoretical interest for decades, however, the systematic research of the topic only prevailed more recently. Purpose - Here we aimed to examine the connection between different schizotypal and non-schizotypal personality traits and verbal creativity in a nonclinical sample. We also investigated the correspondence of two schizotypy inventories, the Oxford-Liverpool Inventory of Feelings and Experiences and a special character configuration of the Temperament and Character Inventory associated with schizotypy. Method - 57 healthy adults (14/43 m/f, mean age 21.51±1.43 years) - took part in the experiment. All participants received a detailed information sheet and gave informed consent prior to participation. Participants completed the Oxford-Liverpool Inventory and the Temperament and Character Inventory to measure both schizotypal and non-schizotypal personality traits. Torrance Test of Creative Thinking was used to measure verbal creativity. Associations between reported measures were examined with correlational and regression analyses. Results and conclusion - Out of the specific Temperament and Character configuration associated with schizotypy (low self-directedness, cooperativeness and high self- transcendence), we only found low self-directedness to be correlated significantly with Oxford-Liverpool schizotypy rates (Self-directedness-schizotypy: r=-.730, p<.01). There was no significant connection between schizotypal traits and verbal creativity. In our sample, the Self-directedness and Reward-dependence character and temperament subscales predicted significantly the verbal creativity level (Self-directedness: b=.330, p=.015; Reward - dependence: b=-.260; p=.049). Based on our results, besides schizotypal traits, other personality measures might be considered in relation to verbal creativity, providing further details to the empirical investigation of creativity. We found low self-directedness to be correlated with Oxford-Liverpool schizotypy rates, however, the sample size was not large enough to test the concurrent validity of the two inventories. Future studies might consider to extend the study sample, preferably to both clinical and non-clinical populations.]

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[Correspondence]

KÖVES Péter

["Let's play cards"; you could say it's a collective gamble that costs a lot of money and the payoff is as uncertain as a dog's dinner. Everyone expects a lot from it: we, the primary care doctors (at present, district, general practitioners and family doctors in the process of metamorphosis), and the patients, who are increasingly waiting outside the doors of our surgeries. ]

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[I hold in my hand LAM issue 5-6. My sincere congratulations to both the previous issues and this double issue. The "outside" and the "inside" are equally valuable. It is a journal with a very fine exhibition. No country much richer than ours can boast of anything like it. The content is also impeccable. The exhibition stands up to all criticism.]

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BÁLINT Géza

[It was with a sincere and eager curiosity to find a solution that I read Dr. Gyula Kincses' article "Thoughts on the financing background of family medicine" (LAM 1991; 9-10: 618-625), and then re-read it again and again. Finally, a very concrete, excellent proposal after all the words, slogans and empty balloons! At last, a well thought-out system which takes into account and tries to take into account not only the various activities of the doctor (prevention, treatment, care), not only the health of the population entrusted to him, but also the training and knowledge of the doctor, the structure of his area of activity, his municipality! At last, a blueprint that can be developed, quantified, tested and used as the basis for a fruitful debate. ]

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[CORRESPONDENCE]

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