Lege Artis Medicinae

[Cephalosporins in the nineties]

GRABER Hedvig1

DECEMBER 23, 1992

Lege Artis Medicinae - 1992;2(12)

[The cephalosporin group is the largest and most widely used family of antibiotics in the nineties. According to their antimicrobial activity, the cephalosporin derivatives are classified as three generations; in Hungary seven parenteral and three oral compounds are available, while some newer ones are under registration. The chemistry and antimicrobial spectra of the cephalosporins are presented, as well as the main problems of bacterial resistance. Pharmacokinetics, adverse effects, and clinical indications of the individual compounds are discussed. The importance of critical use is emphasized.]

AFFILIATIONS

  1. Roussel Tudományos Iroda Budapest

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