Lege Artis Medicinae

[Biological and Pathological Significance of Apoptosis (Programmed Cell Death)]

SZENDE Béla1

JANUARY 29, 1992

Lege Artis Medicinae - 1992;2(01)

[Programmed cell death (apoptosis) basically differs from necrosis regarding its biological significance, the morphological signs and biochemical events. Apoptosis is the result of an active cell function, so-called cell-suicide and it is observable in several biological as well as pathological processes. Enhancement of apoptosis can be achieved in malignant tumors by hormonal treatment. This explains the mode of action of hormones in tumor therapy and also contributes to the alterations in gene regulation leading to apoptosis.]

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  1. Semmelweis Orvostudományi Egyetem I. sz. Kórbonctani és Kísérleti Rákkutató Intézet

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