Lege Artis Medicinae

[Age is Humming a Song]

NAGY Zsuzsanna

DECEMBER 18, 2013

Lege Artis Medicinae - 2013;23(12)

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Further articles in this publication

Lege Artis Medicinae

[Christmas inventory]

BRYS Zoltán

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[Mirror neurons and interpersonality in the paradigm of embodied mind]

HORVÁTH Lajos, SZABÓ Attila

[In this paper, our aim is to scrutinise the psychology and phenomenology of interpersonal relationships from an interdisciplinary viewpoint. This multi-perspectival examination has a key concept: we critically discuss the interdisciplinary dialogues and philosophical appraisals regarding the issue of mirror neurons. Empathy and resonance phenomena have philosophical, psychological, and biomedical importance. Our paper, by applying certain philosophical and empirical results of the overarching paradigm of embodiment, attempts to shed light on several semantic problems, which could come up with respect to the function of mirror-neurons. In conclusion, we would like to attempt to utilise the results of contemporary phenomenology in order to clear some semantic problems, considering the features of mirroring and resonant behaviour.]

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[The Cult of Asclepius ]

MOLNÁR Ella, JÁGER Tibor

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[The Unsettling Dream Pictures of Léon Spilliaert]

NÉMETH István

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[The Triumph of Ideal in the Museum of Fine Arts ]

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We aimed to investigate the association between fluoxetine use and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients. This retrospective case-control study used data extracted from the medical records of adult patients hospitalised with moderate or severe COVID-19 pneumonia at the Uzsoki Teaching Hospital of the Semmelweis University in Budapest, Hungary between 17 March and 22 April 2021. As a part of standard medical treatment, patients received anti-COVID-19 therapies as favipiravir, remdesivir, baricitinib or a combination of these drugs; and 110 of them received 20 mg fluoxetine capsules once daily as an adjuvant medication. Multivariable logistic regression was used to evaluate the association between fluoxetine use and mortality. For excluding a fluoxetine-selection bias potentially influencing our results, we compared baseline prognostic markers in the two groups treated versus not treated with fluoxetine. Out of the 269 participants, 205 (76.2%) survived and 64 (23.8%) died between days 2 and 28 after hospitalisation. Greater age (OR [95% CI] 1.08 [1.05–1.11], p<0.001), radiographic severity based on chest X-ray (OR [95% CI] 2.03 [1.27–3.25], p=0.003) and higher score of shortened National Early Warning Score (sNEWS) (OR [95% CI] 1.20 [1.01-1.43], p=0.04) were associated with higher mortality. Fluoxetine use was associated with an important (70%) decrease of mortality (OR [95% CI] 0.33 [0.16–0.68], p=0.002) compared to the non-fluoxetine group. Age, gender, LDH, CRP, and D-dimer levels, sNEWS, Chest X-ray score did not show statistical difference between the fluoxetine and non-fluoxetine groups supporting the reliability of our finding. Provisional to confirmation in randomised controlled studies, fluoxetine may be a potent treatment increasing the survival for COVID-19 pneumonia.

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