Lege Artis Medicinae

[About books]

SVASTICS Egon

JANUARY 12, 1991

Lege Artis Medicinae - 1991;1(01)

[Short introduction of the book Getting well again]

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Lege Artis Medicinae

[Current issues in oral anticoagulation treatment]

SAS Géza

[Cardiovascular disease is the leading cause of death in civilised countries everywhere. The situation is particularly serious in our country: it is well known that we are one of the countries with the shortest life expectancy in Europe, precisely because of the devastating impact of circulatory diseases. While in the USA, thanks to improvements in living conditions and effective preventive measures, mortality from cardiovascular disease is falling dramatically and is being postponed to later and later years, here at home we can unfortunately expect the situation to deteriorate further in the years ahead.]

Lege Artis Medicinae

[The importance of oral symptoms in the early diagnosis of HIV infection (AIDS)]

BÁNÓCZY Jolán

[Oral lesions of AIDS might occur in every phase of H/V-infection, their importance in the early diagnosis and treatment is significant. The most frequent oral symptoms are: oral Candidiasis, acute necrotizing ulcerative gingivitis (ANUG) and periodontitis, herpetic infections, resistent to the usual therapy. ,,Hairy leukoplakia " of the tongue is characteristic hyperpigmentation of the oral mucosa, Kaposi's sarcoma are frequent symptoms, latter especially in more developed phases (ARC or AIDS) of the disease. Saliva-containing a factor inhibiting HIV-1 infection of human lymphocytes - has minimal importance in the transmission of the disease. Therefore, professional transmission of HIV-infection -, e. g. dental treatment of infected patients keeping the necessary cautions , - present minimal risk. The appropriate treatment of arai lesions of HIV-infected patients may help in maintaining their general health. ]

Lege Artis Medicinae

[The molecular genetics of Duchenne and Becker muscular dystrophy]

FODOR Flóra, PAPP Zoltán

[Duchenne muscular dystrophy, an X-linked inherited disease, is the most common among the severe muscular dystrophies, yet untreatable. lts secondary prevention, however, has become possible by the rapidly developing techniques of molecular biology. The authors describe the latest methods of DNA-diagnosis used, as well as the principles of setting up a diagnostic protocol.]

Lege Artis Medicinae

[The concept of the pathomechanism of ischaemic heart disease]

[The primary atherosclerotic plaque may remain unchanged in extent for a long time and, with the right size of stenosis, results in stable angina pectoris.]

Lege Artis Medicinae

[Family medicine, home care, family care]

ARNOLD Csaba

[General Practice as an independent speciality of medicine has a very special territory, the family care. The family care is a general wish of the society. This special care is continuously made in every fifth-sixth family. ln the author's practice in the autumn of 1989 113families and 16 lonely persons, in 1990 120 families and 18 lonely persons were controlled regularly at home. The family care, the family medicine needs special knowledge and skill. Minimal addicional technical, personal and financial support is requested, burt due to the special care activity the level of medical work increases and it becomes more humanistic, needs of hospitalization decreases and the plus expenditure refunds. Far the better evaluation of family care a more systematic undergraduate and postgraduate teaching and a special research work would be needed.]

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[In memoriam Prof. Dr. Ferenc Garzuly (1937-2021)]

ILLÉS Zsolt, HAHN Katalin, KÁLMÁN Bernadette

[Ferenc Garzuly passed away after a long and productive life at the age of 84. He worked for almost 60 years at the Markusovszky University Teaching Hospital, where primarily led the laboratory of neuropathology and the department of neurology, but transferred to the department of pathology after his retirement. By authoring several books on rare diseases, he greatly enriched the case-based tea­ching approach in medicine. He described the Hun­garian type of transthyretin mutation causing the familial me­nin­go­cerebrovascular amyloidosis phenotype. The presentation of a special phenotype of Fabry disease associated with megadolichobasilar anomaly and a novel mutation in the alpha-galactosidase-A gene is also associated with his name. ]

Lege Artis Medicinae

[CONTROVERSIAL EFFECTS OF NITRIC OXIDE: INTEGRITY AND TOXICITY]

KISS Róbert Gábor, BÉRES Bernát János

[Nitric oxide is a key molecule of the human body. Since its discovery, a library of books and papers have been published on its physiological and pathophysiological role. It is involved in almost all pathological processes. In healthy individuals nitric oxide plays a crucial role in the vascular regulation by protecting against atherosclerosis, myocardial infarction and stroke. In the central nervous system, nitric oxide in its function as a neurotransmitter is responsible for synaptic plasticity, long-term potentiation, memory and a number of neuroendocrine control mechanisms. Furthermore, during inflammation and host defense, macrophages and neutrophils produce nitric oxide that has antibacterial, antiviral, and tumour cell killing activity. In pathologic conditions, however, nitric oxide reacts with superoxide anion to form peroxynitrite that damages the enzymes of the mitochondrial respiratory chain, superoxide-dismutase, reduced glutathion and activates or inactivates signalling molecules. During ischaemia- reperfusion, nitric oxide and peroxynitrite contribute to nitrative/nitrosative stress, DNAfragmentation and consequent polyADP-ribosepolymerase- 1 enzyme activation both in coronary thrombosis and ischaemic stroke.]

Lege Artis Medicinae

[About Books]

FEJÉREGYHÁZI István

[A review of the book written by: László Tringer: "The Healing Conversation"]

Lege Artis Medicinae

[About books]

GRYNAEUS Tamás

[Herbalism - the basics of phytotherapy - Gábor Rácz, Erzsébet Rácz-Kotilla, László Gy.]

Lege Artis Medicinae

[About books]

NAGY Imre

[A review of the book written by Dr. Gaál Csaba : "Surgery"]