Lege Artis Medicinae

[A consultation program for planning insulin therapy]

DEUTSCH Tibor1, WÁGNER János1, TAMÁS Gyula2

MAY 29, 1991

Lege Artis Medicinae - 1991;1(09-10)

[This paper describes a decision support system aimed to assist the day-to-day management of insulin treated diabetic patients based on blood glucose measurements. The therapeutic advices are generated by a multistep procedure involving qualitative reasoning to determine the direction of adjustments and numerical simulation of insulin effect on glycaemia to quantify the extent of control actions to achieve glucose control corresponding to the pre selected targets. The qualitative reasoning module uses meal time oriented glucose balances and distances from the glucose target values to guide the search for appropriate control actions. The simulation module contains a physiologically based glucose-insulin model which generates a 24 hour prediction of the patient's blood glucose profile based on these adjustments which allows the doctor to select the optimal control action from alternatives. The results of a preliminary study to compare the advices given by the system to that of an independent diabetologist are also presented for 11 patients.]

AFFILIATIONS

  1. Semmelweis Orvostudományi Egyetem Számítóközpont
  2. egyetemi docens Semmelweis Orvostudományi Egyetem I. Belgyógyászati Klinika

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