Lege Artis Medicinae - 2012;22(05)

Lege Artis Medicinae

JUNE 15, 2012

[Liver diseases and diabetes mellitus]

WINKLER Gábor

[The liver plays a pivotal role in metabolism. Thus, it is hardly surprising that its acute and chronic diseases may be accompanied by multiple disturbances of the carbohydrate metabolism, and the development of diabetes mellitus - primarily of type 2 diabetes mellitus - may result in structural changes in the liver. This article overviews the main pathogenetic mechanisms of this bidirectional relationship, discusses special considerations of choosing the therapy and highlights special... tovább »

Lege Artis Medicinae

JUNE 15, 2012

[The role of vitamin D in gastrointestinal diseases]

ZÖLD Éva, BODOLAY Edit, ZEHER Zargit, BARTA Zsolt

[The amount of the fat-soluble vitamin D can be reduced by a number of chronic diseases or even obesity. On the other hand, vitamin D itself can also influence the development or course of these disorders. Some gastrointestinal diseases are known to cause vitamin D deficiency, but some observations and studies have also proved that certain gastrointestinal diseases occur more frequently in case of vitamin D deficiency. Moreover, in case of some intestinal tumours even “vitamin D sensitivity”... tovább »

Lege Artis Medicinae

JUNE 15, 2012

[Prevention and treatment of hepatic encephalopathy]

HUNYADY Béla

[As acute or chronic liver diseases progress, liver failure and related hepatic encephalopathy may develop. The latter occurs in more than 70% of patients with hepatic cirrhosis. Because of declining cognitive functions, sleep disturbances, memory problems and impaired motion coordination, this condition can - even in mild form - limit the patient's self-sufficiency and activity and can lead to a decreased quality of life and ability to work. Its most advanced stage, hepatic coma is one of the... tovább »

Lege Artis Medicinae

JUNE 15, 2012

[Insulin dose titration in type 1 diabetes mellitus: A blessing or a curse?]

TAKÁCS Róbert

[INTRODUCTION - Knowing the pharmacokinetic properties of different insulins, useful treatment algorithms can be set up for the majority of our insulin-treated patients. When planning either a human or an analogue basal-bolus regimen, the first task is to determine the daily insulin requirement, followed by determination of the optimal rate of basal and bolus insulins. CASE REPORT - In a 33-year old, moderately obese man with type 1 diabetes who received 180 U daily insulin doses, accumulated... tovább »

Lege Artis Medicinae

JUNE 15, 2012

Lege Artis Medicinae

JUNE 15, 2012

[Asserting basis-bolus principle by analogue insulin preparations in pre-pubertal child with diabetes]

BLATNICZKY László

[INTRODUCTION - The choice of insulin combination therapy in children with type 1 diabetes mellitus is determined basically by the diet as well as the age of the patient. However, life rhythms of individual children are widely different. As a consequence, insulin therapy must be tailored to individual needs, by chosing the optimal one from the available insulin products with different efficacy curves. The aim is, of course, to maintain near-normoglycaemia for years or decades. CASE STUDY - The... tovább »

Lege Artis Medicinae

JUNE 15, 2012