Journal of Nursing Theory and Practice

[The Role of the Study Nurse in clinical trials]

SZABÓ Anita1, KURUCZ-ASZTALOS Nikolett2, DEMETER Zsuzsanna3, PIKÓ Béla4, DANK Magdolna5

FEBRUARY 28, 2021

Journal of Nursing Theory and Practice - 2021;34(1)

[The aim of this study: A brief summary of the role of the study nurse in the drug clinical trial. Based on the available literature and practical experience gained on clinical trials in cancer patients, we analyzed the role and expectations of study nurse. Due to a lack of knowledge about clinical trials, nurses are not or reluctant to participate in these. In practice, following the direction of clinical trial protocol, demanding nursing activity and accurate documentation are the basic requirements. If the above requirements are met, the study nurse becomes an indispensable member of the study group.]


  1. Békés Megyei Központi Kórház Pándy Kálmán Tagkórház, Megyei Onkológiai Központ, Gyula
  2. Centrum Pharma Kft., Gyula
  3. Központi Kórház Pándy Kálmán Tagkórház, Belgyógyászati Osztály – Kardiológia, Gyula
  4. Békés Megyei Központi Kórház Pándy Kálmán Tagkórház, Megyei Onkológiai Központ, Gyula
  5. Semmelweis Egyetem, Belgyógyászati és Onkológiai Klinika, Budapest



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[In the early part of the 20th century in Hungary, the nursing and caregiver profession has evoled considerably, including the introduction of specializations. Pediatrician Sándor Szana, considered by literature to be founder of the training of Pediatric Caregivers, offered the first lectures in 1904 for 5 females. Later the National Stephanie Alliance came into being as a key organisation in this field from 1915. On the initiative of Pediatrician Pál Heim, the Stephanie Alliance started a Pediatric Caregiver training in 1916. Thus, the first such childcare nursing specialization was named after Pál Heim MD, and the nurses who graduated were called Heim-Nurses. In addition to the Heim-Nurses, the authors of this paper also present the activities of the Calmette Nurses. Since this period, tuberculosis (TB) has been one of the leading causes of death in Hungary.]

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[Aim of the study is to assess the Quality of Life of patients with rheumatoid arthritis, who are living with chronic pain and explore what kind of experiences and attitudes they have to the music therapeutic pain relief. In the whole sample was 60 women with rheumatoid arthritis, whereof 12 people were admitted to the intervention group and 10 people to the control group. We examined socio-demographic, psychological Quality of Life variables, attitude to music and about their music therapy experiences. For the intervention group and the control group, data were recorded twice, before and after training. Statistical analysis was performed with SPSS software package 23, covering descriptive statistics, analysis of variance, paired t-test and correlation analysis (p<0,05). The psychological Quality of Life indicators of the studied RA group lag behind the population average, its members experience negative emotions, more depressed mood. The intervention using music therapy elements had the potential mainly to influence the participants’ mood positively and reduce the subjective experience of pain. Even a shorter-term intervention (13 group sessions) can trigger positive changes in the participants: improve their mood and mitigate the intensity of pain.]

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[The aim of this study was to investigate the incidence of VAP in open and closed suction techniques and to determine whether closed suction techniques had altered the duration of combination antibiotic use. Quantitative, retrospective study was performed at the Central Anes­thesiology and Intensive Care Unit. A non-randomized, targeted expert study is aimed at patients in intensive care units with evidence of respiratory-related pneumonia. Data were collected from hospital records, the hospital pharmacy IT system, the NNSR system. Descriptive and mathematical statistical methods(p<0,05) were used to evaluate the results. Mean of ventilated days was 9.95±3.35. VAP was reported at an average of 4.95±2.29 days and antibiotic treatment lasted for 8.00±2.66 days. The suction technique showed with the number of intensive care days, the number of ventilation days, the average number of VAPs, and the treatment with antibiotics. The introduction of a closed suction alone did not reduce the incidence of VAP and the use of antibiotics. APN plays an important role in uncovering the risk factors for VAP and preventing its development, which ultimately leads to a reduction in mortality.]

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[Restless leg syndrome, more recently renamed Willis-Ekbom disease, is a condition that disrupts sleep and occurs more frequently in the pregnant population. In women with restless legs syndrome, night cramps, and excessive daytime sleepiness were more frequent. This syndrome is a common condition that is frequently unrecognized, misdiagnosed and poorly managed. Communication aim was to present a broad summary of the latest results of international literature. Severe and untreated syndrome not only negatively affects the quality of life of patients, e.g. insomnia, excessive daytime fatigue, decreased concentration and mood, avoidance of activities requiring limited mobility, but also has a negative effect on the onset of general disease (increased anxiety and depression, cardiovascular disease and stroke).]

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Journal of Nursing Theory and Practice

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[Aim of the research: To assess the occupational duties and responsibilities of nurses in relation to clinical trials in Hungary. Research and sampling methods: Self-administered questionnaire was used among the colleagues working in the field of clinical trial and IBM SPSS 22.0 software using descriptive statistical methods was performed. Results: It was found that the majority of nurses complete the duties of a study coordinator and the task of a study nurse simultaneously. They were involved in everyday activities that characterise the assistance of patients and in the management of paper-based documentation during clinical trials. Lack of knowledge in English language was identified for the reason of reduced-functionality of nurses in 59 cases. Conclusions: nurses have complex responsibilities, although they meet the requirements when it comes to the professional tasks and documentation obligations, but in the case of more complicated professional challenges nurses get fewer opportunities, mainly because of their poor English skills.]

Clinical Neuroscience

Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

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