[Stroke is a serious health problem that has a significant impact on health-related quality of life. Despite the increasing popularity of measuring quality of life among patients, it is not routinely measured in clinical practice, and therefore little is known about how well clinical measures reflect quality of life after stroke. The aim of this study was to investigate the quality of life of patients with acute ischaemic stroke.

For the prospective study, patients diagnosed with acute ischemic stroke at the Neurology Clinic of the Clinical Center of the University of Pécs were selected through convenience sampling between June 2022 and May 2023. Based on the treatments, patients were divided into three groups: mechanical thrombectomy (MT), intravenous thrombolysis (IVT), and standard care (SC). Modified Rankin Scale (Pre-mRS, Follow-up mRS), NIH Stroke Scale (NIHSS), and European Quality of Life 5 Dimensions Scale (EQ-5D-5L) were used in the research. Descriptive statistics, paired T-tests, Wilcoxon tests, McNemar tests and Pearson correlation analysis were applied for the analysis (SPSS 25.0; p <0.05).

A total of 198 participants (115 males, 83 females) took part in the study (MT: 50, IVT: 69, SC: 79). The Pre-mRS and follow-up mRS values indicate that the majority of patients in all three groups fell into the mild category (Pre-mRS: 176 participants; 88%, follow-up mRS: 158 participants; 80%). There was a significant improvement in NIHSS scores in all three groups (IVT: 4.36 vs. 1.57, p<0.001; MT: 8.98 vs. 4.50, p<0.001; SC: 4.38 vs. 2.84, p<0.001). The EQ-5D-5L value also significantly increased for all groups (IVT: 0.82 vs. 0.88, p<0.001; MT: 0.63 vs. 0.73, p<0.001, SC: 0.76 vs. 0.80, p=0.014). Patients admitted with lower NIHSS values reported better quality of life at the end of our study (r: -0.43451).

At 30 days, significant improvement was observed in MT, IVT and SC groups when measured with EQ-5D-5L, but the extent of improvement was highest in the MT group.]

[The aim of the research study was to get a better picture of the patient’s quality of life with Huntington’s disease and their caretaker’s. One of the main topics of the investigation was the family, because taking care of a Huntington’s patient can have a big impact on their lives. Our further concern was to introduce the concept for the families and test their open mindedness, if they would take assistance from nurse graduates to make the patient’s medical journey shorter and help with their everyday life challenges. 

The cross-sectional research was done by validated tests, as well as, self-made tests which contained socio-demographic data and questions regarding the disease. The trial took place at Semmelweis University, at the Institute of Genomic Medicine and Rare Disorders in collaboration with the patients and their families. 

According to the patients, their life quality is affected more physically than their mental health. The experiment showed that the disease has a big impact on the quality of life of the family members. The family members would be more open in regards to accepting help from advanced practice nurses. 

Huntington’s disease has a negative impact on the quality of life of the patients and their families. It would be adequate to study if the provided help of advanced practice nurses could improve their quality of life. ]

[The purpose of the study is to investigate the quality of life of young adults in relation to oral health and how smoking affects this. The aim is to explore the differences in oral health-related quality of life between smokers, non-smokers, and quitters in a given age group.

The survey was conducted using a self-designed online questionnaire that included the Oral Health Impact Profile (OHIP-14) questionnaire. The survey was conducted from May 01 to June 30, 2023, using a nonrandom sampling method that relied on easily accessible subjects. Data were processed and analysed using IBM SPSS 20.0 statistical software, descriptive statistics, Kruskal-Wallis test, and Spearman’s rank correlation analysis (p<0.05). 

Based on the 317 assessable responses, smokers had a higher average OHIP-14 total score than non-smokers and quitters, but there were no significant differences in oral health-related quality of life between the groups (p=0.540). Four self-reported questions were added to the OHIP-14 questionnaire: dissatisfied with the colour of their teeth; afraid of communicating with others without seeing their teeth being seen; afraid of having a serious oral problem; afraid of losing their teeth. These issues are highly correlated with the OHIP-14 questionnaire and fear of oral lesions appears to be present among smokers.

Young adults do not yet show a significant deterioration in oral quality of life due to smoking, but additional questions are worth considering to assess the quality of life in smokers.]

[The high blood pressure disease is one of the primary risk factors for the development of other cardiovascular diseases. The aim of the present study was to assess the medication habits, sleep quality, and quality of life of patients aged 45 and older living with hypertension.

Our study was a quantitative descriptive cross-sectional survey conducted in 2022 in the form of an online questionnaire among patients aged 45 and older suffering from hypertension (n=143). The data collection tools included the Morisky Medication Adherence Scale (8 items), the Pittsburgh Sleep Quality Index, EQ-5D-5L, and a self-designed questionnaire.

Lower age was associated with higher levels of medication adherence (R=-0.36; p=0.024). Patients who regularly visited their general practitioner showed more consistent medication intake (p=0.048). Adequate sleep quality positively influenced the quality of life (p<0.001).

Regular visits to the general practitioner not only facilitate medication adherence but also provide an excellent opportunity for patient education and health promotion. Therefore, it has paramount importance to draw the attention of hypertensive patients to the role of regular check-ups with their general practitioner, which can contribute to the prevention of complications arising from hypertension.]

[Background: The increased number of cancer survivors and the recognition of physical and psychosocial challenges, present from cancer diagnosis through active treatment and beyond, led to the discipline of cancer survivorship.]