Hungarian Radiology

[Prevention of thrombotic complications in vascular interventional procedures]

HORVÁTH László, BATTYÁNY István, ROSTÁS Tamás, HARMAT Zoltán, BODROGI Gabriella, RADICS Éva

JUNE 10, 2005

Hungarian Radiology - 2005;79(03)

[Procedures of vascular interventional radiology is linked inevitably a certain amount of risk of thrombotic complications, like intimal and vascular wall injuries, increased thrombotic risk caused by the catheter itself, etc. The first approach of thrombotic prevention was achieved by acetyl salicylic acid in case of peripheral arteries, this treatment was later replaced by long-term anticoagulation. Opportunities were provided by the recognition of risky blood characteristics in relation to thrombotic complications. Consequently, a well performed preparation and premedication of the patients could reasonably decrease the risk. The most important steps are the cessation of smoking, normalization of hemoconcentration and antithrombotic premedication. Better understanding of the nature of atherosclerotic progression led to the introduction of long-term fibrinolytic inhibition therapy. In the past decades beside patients with vascular stenosis, the oncology patients are also treated by different radiological interventions, like intraarterial chemotherapy and chemoembolization. The use of several-day-long infusion represent a new challenge, the treated vessels, the lumen and the surface of the catheter must be prevented of thrombosis. For this purpose a few suitable drugs can be applied with mild anticoagulant and fibrinolytic stimulating effect. We use the sodium pentosan polysulphate.]

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