Hungarian Radiology

[Pictures to the past Methodological possibilities in the palaeoradiology]

ALIDA Lilla Kristóf, BARTA H. Miklós, PETRIK Anikó, PAP Ildikó, PÁLFI György, FORNET Béla, FORRAI Gábor

FEBRUARY 20, 2004

Hungarian Radiology - 2004;78(01)

[INTRODUCTION - The radiology as a method is useful not only in the field of the traditional medicine, but in the historic anthropology examining the ancient human remains, and in the palaeopathology examining the pathological changes of the ancient human remains. The aim of our study was the correction of the palaeopathological methods and the radiological diagnosis of the ancient pathological remains. MATERIAL AND METHODS - Approximately 25 specimens originating from the Avar-, the Hungarian Conquest Period and from the Arpadian Age with pathological changes were examined. Besides these 11 naturally mummified individuals were examined by radiological methods, too. The X-ray examinations were done at the Department of Radiology of the National Medical Centre, in Budapest. RESULTS - Vertebral changes, pulmonary tuberculosis and traumatic lesions were found on the mummified individuals. The most frequent changes of the bone alterations were traumas: fractures of the ulna, clavicule, ribs, and trephanation of the skull. Several degenerative changes of the vertebral columns and of the articulation surfaces were detected (osteophyta, spondylosis, arthrosis). The rheumatoid arthritis, Paget-disease, facies leprosa, and the traces of vertebral tuberculosis should be mentioned among the rare pathological disorders. CONCLUSIONS - Since there are no sufficient palaeoradiological methodological references, it was necessary to develop new methods for X-ray examinations.]



Further articles in this publication

Hungarian Radiology

[Theoretical basis of tumor staging The significance of imaging in oncological diseases]


[The general goal for staging patients with any cancer is to determine the overal extent of disease prior to choice of therapy. It has been well documented that biological behavior of any cancer and, therefore, the prognosis of the patient is strongly linked to the extent of the tumor, the presence or absence of lymphatic dissemination as well as systemic metastases. The staging systems have undergone a number of modifications. Classifications of TNM system identifies the depth of tumor invasion (T), the status of regional lymph nodes (N) and the distant metastases. These three parameters are then incorporated into the final clinical stage. There are further modifications which influence the patient survival, e.g. biological, genetical, hystological factors, tumor grade. All cancer cells show dysregulation of cell cycle controll. As the cancer proliferates and the tumor reaches approximately 1-2 mm in diameter further growth recquires the development of new blood vessels (neo-angiogenesis). Intensity of tumor growth has a prognostic influence to the patient's life and depends on the tumor doubling time, which classifies tumors into slow, intermadiate and rapid growing types. The diagnostic impact of imaging is based on the ability of a technique to detect and evaluate the cancer accurately. The very high accuracy and reproducibility of cross-sectional imaging, paticularly computed tomography (CT) and magnetic resonance imaging (MRI) make these methods extremely important in the detection, staging and in the evaluation of the tumors. The revolutionary advances in detection and treatment of malignant disease have led to an increasing role of the radiologist as a member of the multidisciplinary cancer team.]

Hungarian Radiology



Hungarian Radiology

[Candida esophagitis]

SZÁNTÓ Dezső, SZŰCS Gabriella, DITRÓI Edit

[INTRODUCTION - 97-98 percent of upper gastrointestinal mycoses are caused by candida albicans infections. Two cases of candida oesophagitis is reported in female patients with bronchial asthma. CASE REPORT - The patients were treated with steroid drugs due to the asthma. Esophageal barium study in a 48 year old female showed fine multiple rounded radiolucent aphthoid lesions, which fused after six weeks and resulted an aphthoid-shaggy esophagus. In a 55 year old patient double-contrast plain films presented cobblestone, alias snakeskin esophagus and foamy cardia. CONCLUSION - Radiographic signs of candida esophagitis are not pathognomic but correctly demonstrate extension of fungal infection into esophageal wall. Definitive diagnosis can be proved by histological and microbiological examinations.]

Hungarian Radiology

[Cornell Seminar]


Hungarian Radiology

[Future planning of radiology before joining the EU]


All articles in the issue

Related contents

Clinical Neuroscience

Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

JARABIN András János, KLIVÉNYI Péter, TISZLAVICZ László, MOLNÁR Anna Fiona, GION Katalin, FÖLDESI Imre, KISS Geza Jozsef, ROVÓ László, BELLA Zsolt

Although vertigo is one of the most common complaints, intracranial malignant tumors rarely cause sudden asymmetry between the tone of the vestibular peripheries masquerading as a peripheral-like disorder. Here we report a case of simultaneous temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting as acute unilateral vestibular syndrome, due to the reawakening of a primary gastric signet ring cell carcinoma. Purpose – Our objective was to identify those pathophysiological steps that may explain the complex process of tumor reawakening, dissemination. The possible causes of vestibular asymmetry were also traced. A 56-year-old male patient’s interdisciplinary medical data had been retrospectively analyzed. Original clinical and pathological results have been collected and thoroughly reevaluated, then new histological staining and immunohistochemistry methods have been added to the diagnostic pool. During the autopsy the cerebrum and cerebellum was edematous. The apex of the left petrous bone was infiltrated and destructed by a tumor mass of 2x2 cm in size. Histological reexamination of the original gastric resection specimen slides revealed focal submucosal tumorous infiltration with a vascular invasion. By immunohistochemistry mainly single infiltrating tumor cells were observed with Cytokeratin 7 and Vimentin positivity and partial loss of E-cadherin staining. The subsequent histological examination of necropsy tissue specimens confirmed the disseminated, multi-organ microscopic tumorous invasion. Discussion – It has been recently reported that the expression of Vimentin and the loss of E-cadherin is significantly associated with advanced stage, lymph node metastasis, vascular and neural invasion and undifferentiated type with p<0.05 significance. As our patient was middle aged and had no immune-deficiency, the promoting factor of the reawakening of the primary GC malignant disease after a 9-year-long period of dormancy remained undiscovered. The organ-specific tropism explained by the “seed and soil” theory was unexpected, due to rare occurrence of gastric cancer to metastasize in the meninges given that only a minority of these cells would be capable of crossing the blood brain barrier. Patients with past malignancies and new onset of neurological symptoms should alert the physician to central nervous system involvement, and the appropriate, targeted diagnostic and therapeutic work-up should be established immediately. Targeted staining with specific antibodies is recommended. Recent studies on cell lines indicate that metformin strongly inhibits epithelial-mesenchymal transition of gastric cancer cells. Therefore, further studies need to be performed on cases positive for epithelial-mesenchymal transition.

Clinical Neuroscience

Valproic acid associated pleuropericardial effusion: case report

DEMIR Figen Ulku

Introduction - Valproic acid is an effective antiepileptic and mood stabilizer used in the treatment of many neurological and psychiatric disorders. Although there are frequently seen side effects, effusions between layers of pleural and pericardial membranes are rare to be seen. Case - Pleuropericardial effusion was detected in a 23 years old woman who was under valproic acid treatment because of epileptic seizure. After 1 year of valproic acid treatment, patient complained of dyspnea. As all the researches intended on etiology were usual, valproic acid has been thought to be responsible for the matter. Control examination after 1.5 months regarding the end of treatment revealed complete recovery of pleuropericardial effusion. Discussion - Pleural and pericardial effusions are rarely seen complications related to the use of valproic acid. It must also be kept in mind that valproic acid causes a potential for such side effects which can be blamed etiologically when the other possibilities for patients are excluded.

Lege Artis Medicinae

[Five-year results of „Comprehensive Health Screening of Hungary 2010-2020”]

KISS István, BARNA István, DAIKI Tenno, DANKOVICS Gergely

[The „Comprehensive Health Screening of Hungary 2010-2020” have finished the 5th jubilee season. Int he past five year the program was working succesfully as a model for the primer and secondary prevention. The results of comprehensive screening have shown caracteristic picture about the health of population, and many people received education, informations about health protection, prevention and healthy lifestyle. More than 900 places, 7 millions of filled risk queries, 112 000 people’s comprehensive screening and 250 000 counsellings are the summary of activities. Some 200 000 people received the information pack. Significant is the familiar occurence of tumors and cardiovascular diseases, that means 20% of prevalence in test subjects. We are obese, smokers, physically inactive, our health behavior is poor. The improvement of the populational health care activity is among the strategical plans of health politics, and it is badly needed based on the results of MÁESZ Program.]

Lege Artis Medicinae

[Introducing a new, personalized multistep cognitive behavioral therapy for obesity]


[Two thirds of Hungary’s adult population live with excess weight. Obesity itself is a chronic disease that is a risk factor for many other chronic diseases, and therefore adequate treatment is of public health impor­tance. Although behavioral therapy is one of the evidence-based approaches to treating obesity, its long-term effectiveness is not well-established. That is why intensive work has been done over the past decades to furth­er develop behavioral therapy. A recent example of this is a multi-step treatment program that can be implemented in a number of settings of the health care system regardless of the excess weight and the presence of comorbid conditions of obesity. This treatment program is based on classical behavioral treatments and new cognitive-behavioral treatments of obesity and, in addition to the acquisition of long-term lifestyle-changing skills, contributes to the treatment of obesity through the development of a mind-set for long-term weight control. The purpose of this study is to present the program.]

Clinical Neuroscience

[Surgical treatment of epilepsy]


[In this article the possibilities, indications, methods and results of surgery in epilepsy are summarized in general with the Hungarian experience emphasized. Surgery may provide effective treatment in about 5-10% of the epileptic population. Surgical solution nowadays became an essential treatment in medial temporal epilepsy, if hippocampal sclerosis or other lesion is present, in therapy resistent lesional extratemporal epilepsies and in catastrophic childhood epilepsies if the epileptic disorder is restricted to one hemisphere (Rasmussen syndrome, hemimegalencephaly, Sturge-Weber disease and posttraumatic or postencephalitic hemispherial epilepsies). The algorhythms of the presurgical evaluation and the current methods for study the pacemaker area, forbidden zones, and hemispherial functions are treated. The currently used type and techniques of surgery, such as lesionectomy, temporal lobe resections, hemispherotomy, callosotomy, multiple subpial transsections and their indications are described. The newest surgical approaches, as deep brain stimulation, vagal nerve stimulation, and irradiation techniques are also briefly touched. Lastly, we deal with prognostical factors of the surgical outcome, reasons of surgical failures and complications. In a brief chapter the importance of postsurgical rehabilitation is emphasized.]