Hungarian Radiology

[Farewell to dr. József Soós 1926-2009]

VICZENA Pál

OCTOBER 20, 2009

Hungarian Radiology - 2009;83(03)

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Hungarian Radiology

[Ways of imaging the expression of vascular endothelial growth factor and its receptor]

KOROM Csaba, KARLINGER Kinga

[The vascular endothelial growth factor (VEGF) and its receptors (VEGFR) signal-transduction pathway play a key role in the regulation of angiogenesis. It was originally isolated as a selective mitogen for endothelial cells and as a powerful vascular permeability increasing factor. The vascular imaging techniques make the quantification and localization of blood vessels possible. They have been used to assess blood flow, oxygenation, and vascular permeability. Also, they can be used to examine the molecular and cellular difference in the vascular wall. To evaluate tumour vascularity, a multimodality approach is expanding. VEGF as the primary mediator for vascular-permeability is indirectly measurable with DCE-MRI (dynamic contrastenhanced MRI). MRI investigation can determine the ratio of deoxyhemoglobin/oxyhemoglobin in order to localize the hypoxic regions in vivo (BOLD [blood oxygen-level dependent] sequence and OMRI [Overhauser MRI]). In molecular MRI (mMRI), contrast agent-mediated alteration of tissue relaxation times can allow for the detection and localization of molecular disease markers. To localize the expression of VEGFR with SPECT and PET, antibodies and VEGF isoforms can be marked with isotopes. VEGFR is an excellent candidate for targeted ultrasound imaging since it is almost exclusively expressed on activated endothelial cells. Optical imaging is a relatively cheap method suitable so far primarily for small animal studies.]

Hungarian Radiology

[16th International Symposium of Pediatric Radiology Section of the Society of Hungarian Radiologists - Szeged, September 10-12th, 2009.]

VÁRKONYI Ildikó

Hungarian Radiology

[Interventional neuroradiological treatment of a symptomatic basilar artery stenosis in the background of recurrent brainstem transient ischemic attack]

LOVÁSZ Rita, NÉMETH Csilla, LÁZÁR István, VALIKOVICS Attila

[INTRODUCTION - Symptomatic stenosis of the basilar artery carries high risk of brainstem stroke. In case of acute thrombotic occlusion of the basilar artery the mortality is over 70%. Besides best medical treatment, angioplasty was employed for 30 years previously, but the results were only acceptable after the advent of flexible intracranial stents. We report our case to call attention to the availibility of this interventional neuroradiological procedure. CASE REPORT - A 64 years old male patient was admitted to our hospital with intermittant diplopia. 90% stenosis of proximal basilar artery was reported by DSA. After balloon dilatation, intracranial stent was placed into the lesion. Symptoms have not recurred three months following the intervention. Control TCD and MR-angiography were performed, and good blood flow ratio was detected in the vertebrobasilar system. CONCLUSION - In the background of recurrent brainstem TIA a basilar artery stenosis has to be searched because the development of a definitive brainstem stroke can be prevented by interventional neuroradiological procedure.]

Hungarian Radiology

[Further stories about Professor Zoltán Zsebők - Another follower’s remembrance]

MESTER Ádám

Hungarian Radiology

[Experimental e-Learning course in the further training of Hungarian radiographers]

VANDULEK Csaba, TÓTH Lilla, DONKÓ Tamás, PAVLIKOVICS Gábor, BOGNER Péter, CSONTOS Éva, REPA Imre

[The growth in digital media technology within the past decade has strengthened e-Learning’s position in education. Traditional teaching methods are changing: from teacher to moderator and passive learner to active learner. A pilot e-Learning course in MR angiography (MRA) has been undertaken with Hungarian radiographer participants. The e-Learning course consisted of three phases covering basic MRA physics and technical aspects, advanced MRA techniques and concluding with an assessment work. The promising results suggest that e-learning may be a feasable method for the continuing professional development of Hungarian radiographers.]

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