Hungarian Radiology

[European Congress of Pediatric Radiology Edinburgh, 4-7 June 2008]

VÁRKONYI Ildikó

DECEMBER 15, 2008

Hungarian Radiology - 2008;82(07-08)

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Hungarian Radiology

[A Deliberate Violation of Symmetry My Entry for the Ig Nobel Prize]

LOMBAY Béla

Hungarian Radiology

[Radiology of pancreas: review from the last year - Gastro Update 2007]

FORRAI Gábor

[PURPOSE - To demonstrate the recent results in radiological diagnostics of pancreas, and the actual place of the imaging and interventional methods. METHOD - Systematic review of the most recent articles from the last year in the following subjects: acute, chronic and autoimmune pancreatitis, pancreatic cancer and other tumors, PET and special imaging problems in pancreas transplantation. RESULTS - Annually, experience in pancreatic diagnostical methods are accumulating rapidly. Therefore, there is a continuous change in the examination algorithm with new diagnostic and therapeutic modalities making their way into the daily routine. Some of the algorithms become obsolete within a few years and their further application is considered mismanagement. Some other methods become obligatory steps in the diagnostics. These are the reasons why up-to-date knowledge of the literature is mandatory.]

Hungarian Radiology

[Role of contrast enhanced ultrasound in clinical practice]

HARKÁNYI Zoltán

[Ultrasound contrast agents consist of micro bubbles which can be visualized during their short intravascular and parenchymal transit time. An US system with special software, a small amount of intravenous contrast agent and a skilled operator is necessary to produce a successful study. This method can also be introduced into the clinical practice in our country. Careful indications and well performed studies can reduce the number of unnecessary CT and MR studies and biopsies. Contrast enhanced US has special clinical significance in the detection and characterization of focal liver masses, monitoring drug and local treatment effects of different abdominal tumors and in the case of injury of abdominal parenchymal organs.]

Hungarian Radiology

[Evaluation of cystic renal masses with MDCT]

BATA Pál, MIKUSI Regina, KARLINGER Kinga, BÉRCZI Viktor, SZENDRŐI Attila, ROMICS Imre

[Modern CT and MRI scanners can give an exact and rapid diagnosis in the case of most cystic renal masses. Dilemma in their diagnosis is whether or not the changes need surgical intervention. The question of follow-up is decided with the use of the Bosniak classification. To characterize the cystic changes excellent quality, multiphasic MDCT examination is necessary with the following parameters: 80-120 mls. of non-ionic iodinated intravenous contrast material given with an injector at 3 ml/sec flow-rate with saline flush technique, unenhanced and post-contrast scans obtained at 35 and 70 seconds, with more scans at 120-300 seconds, as deemed necessary. A collimation of 16x1.5 mm with an overlap of 50% should be aimed for. Through the primary data we perform a reconstruction of 2 mm, with an option to create volume-rendered image sin the post-processing phase, as necessary. With the help of this CT protocol we can measure the different criterions of Bosniak classification in the cystic masses like minimal, smooth or irregular wall thickening, with or without enhancement. We can recognize hairline thin or thickened septa, fine or irregular (thick or nodular) calcifications, solid component with or without contrast enhancement. Using these criteria each cystic mass can be assigned to a Bosniak cystic category (I, II, IIF, III and IV)]

Hungarian Radiology

[High resolution sonography for the examination of peripheral nerves]

JOSEF Böhm

[High-frequency sonography is an important method for the imaging of the peripheral nerves, even though it is rarely used. For the examination of superficially located nerves, currently available transducers with frequencies between 12-17 MHz offer a better axial resolution than even MRI. Sonography is superior to MRI especially for the examination of nerves of the upper extremity. Main indications for the sonography of the nerves are entrapment syndromes, traumatic injuries of the nerves, tumors, polyneuropathies and sonographically-guided interventions. The sensitivity of sonography and electrophysiology in the diagnosis of carpal tunnel syndrome and cubital tunnel syndrome are comparable. The combination of ultrasonography with electrophysiological studies increases the diagnostic yield in carpal and cubital tunnel syndromes. Sonography provides information for planning of peripheral nerve surgery and is helpful in evaluating postoperative complications. In selected cases, sonography can detect nerve lesions that require operative therapy earlier than electrophysiology. With technical enhancements, highfrequency ultrasonography is gaining increasing importance in the routine diagnostics of peripheral nerves lesions.]

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[Multiple sclerosis (MS) is typically a disease of young adults. Childhood MS can be defined in patients under 18 years of age, although some authors set the limit un­der the age of 16 formerly known as “early-onset multiple sclerosis” or “juvenile multiple sclerosis”, seen in 3-5% of all MS patients. Nowadays, owing to ever-evolving, better diagnostic tools and well-traced, strictly defined diagnostic criteria, childhood MS is showing an increasing incidence worldwide (0.05-2.85/100 000). MS is characterized by recurrent episodes of the central nervous system with demyelination separated in space and time. In childhood almost exclusively the relapsing-remitting (RR) type of MS occurs. Based on experience in adults, the goal in the pediatric population is also the early diagnosis, to initiate adequate DMT as soon as possible and to achieve symptom relief and good quality of life. Based on efficacy and safety studies in the adult population, inter­feron β-1a and glatiramer acetate were first approved by the FDA and EMA for the treatment of childhood MS also. The increased relapse rate and rapid progression of childhood MS and unfavorable therapeutic response to nearly 45% of the first DMT necessitated the testing of more effective and second-line drugs in the population under 18 years of age (PARADIGMS, CONNECT). Although natalizumab was reported to be effective and well-tolerated in highly active RRMS in childhood, evidence based studies were not yet available when our patients’ treatment started. In this article, we report on the successful treatment of three active RRMS patients with individually authorized off-label use of natalizumab.]