Hungarian Radiology

[A world champion radiologist - Sport success of Zsuzsanna Kis]

LOMBAY Béla

DECEMBER 20, 2004

Hungarian Radiology - 2004;78(06)

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Hungarian Radiology

[Metastasis of the large bowel from gastric signet-ring cell carcinoma - Case report]

TÓTH Géza, LUKOVICS Péter, LÁHM Erika, KOVÁCS Margit

[INTRODUCTION - Metastatic tumor of the colon is extremely rare. It could mimic inflammatory bowel disease or ischemic colitis. CASE REPORT - A 59-year-old female underwent gastrectomy because of primary signet-ring cell carcinoma of the stomach in 1999. In November 2003 follow-up CT detected circular and segmental thickening of the wall of the transverse colon with significant targetlike contrast enchancement of the inner layers. Colonoscopy was performed but due to the significant stenosis of the transverse colon, the tumor was not properly examined. Biopsy was taken from the beginning of the stenosis, which did not prove neither specific inflammation or malignancy. Barium enema and virtual colonoscopy was performed. There was mild dilatation of the stenotic part and mucosa seemed to be intact by virtual colonoscopy. Barium enema showed significant stenosis and polypoid alteration of the mucosa in the right part of the colon. There was also an asymmetric bowel wall thickening of the flexura lienalis. Because of subileus the patient was operated on, and an extended right hemicolectomy was made. The histology of the specimen verified secondary signet-ring cell tumor of the colon. CONCLUSION - In case of multiple circular and segmental thickening of the wall of the colon, with striking thickening of the enchancing inner layer with decreased contrast enhancement in the outer layer (target pattern) on the CT, the metastasis of the large bowel should be considered.]

Hungarian Radiology

[Shrinking borders of our globalized world - Interwiew with Indian radiologist Nirvikar Dahiya]

HARKÁNYI Zoltán

Hungarian Radiology

[70th Anniversary of the Greek Radiological Society]

LOMBAY Béla

Hungarian Radiology

[Recent advances in the radiology of colon cancer - Onco Update 2004]

KOLLÁR Attila

[The recent literature of colon cancer imaging, colonic stenting and the interventional treatment of colorectal liver metastases is overviewed. The introduction of virtual colonoscopy in the diagnosis of colon cancer drew attention in the last years and it is one of the most rapidly developing method. Several new publications was published about CT and MR colonography in the past one and half year. Nowadays, beside the double contrast barium enema and the colonoscopy (as gold standard), CT and MR colonography plays more and more important role. These methods can be applied only with multislice CT and modern MR machines equipped with appropriate softwares. Since these equipments are available only in limited number in Hungary, these methods has not been used in the daily practice. Development of interventional methods, like stenting of obstructive colon tumor and the percutaneous and intraarterial interventional treatment of colorectal metastases play more and more important role in the therapy, as indicated in the literature.]

Hungarian Radiology

[19th Sopron Ultrasound Days]

VARGA Tamás

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Clinical Neuroscience

[Earlier and more efficiently: the role of deep brain stimulation for parkinson’s disease preserving the working capabilities]

DELI Gabriella, BALÁS István, KOMOLY Sámuel, DÓCZI Tamás, JANSZKY József, ASCHERMANN Zsuzsanna, NAGY Ferenc, BOSNYÁK Edit, KOVÁCS Norbert

[Background – The recently published “EarlyStim” study demonstrated that deep brain stimulation (DBS) for the treatment of Parkinson’s disease (PD) with early fluctuations is superior to the optimal pharmacological treatment in improving the quality of life and motor symptoms, and preserving sociocultural position. Our retrospective investigation aimed to evaluate if DBS therapy was able to preserve the working capabilities of our patients. Methods – We reviewed the data of 39 young (<60 years-old) PD patients who underwent subthalamic DBS implantation at University of Pécs and had at least two years follow-up. Patients were categorized into two groups based on their working capabilities: Patients with active job (“Job+” group, n=15) and retired patients (without active job, “Job-” group, n=24). Severity of motor symptoms (UPDRS part 3), quality of life (EQ-5D) and presence of active job were evaluated one and two years after the operation. Results – As far as the severity of motor symptoms were concerned, similar (approximately 50%) improvement was achieved in both groups. However, the postoperative quality of life was significantly better in the Job+ group. Majority (12/15, 80%) of Job+ group members were able to preserve their job two years after the operation. However, only a minimal portion (1/24, 4.2%) of the Job- group members was able to return to the world of active employees (p<0.01, McNemar test). Conclusion – Although our retrospective study has several limitations, our results fit well with the conclusions of “EarlyStim” study. Both of them suggest that with optimal timing of DBS implantation we may preserve the working capabilities of our patients.]

Lege Artis Medicinae

[In vitro diagnostic medical testing laboratories and EU standards; basic elements]

DEBRECZENI Lóránd, FEKETE Mátyás, VÁSÁRHELYI Barna

[In the “in vitro diagnostic testing medical laboratories” particular attention should be paid to the confidental and reliable operation as to 60-75% of the information for medical decisions are derived from laboratory tests. The high-quality laboratory work is based on the standards created by the national professional boards. Laboratories in Hungary (as any other country around the world) should comply with the various directives and/or standards set out requirements: MSZ EN ISO 15189:2013, MSZ EN ISO 22870:2006, MSZ EN ISO 15197:2013, Guide to the Expression of Uncertainty in Measurements (GUM), guidelines of the International Union of Pure and Applied Chemistry (IUPAC), etc. Special attention should be devoted to the quality of the work (internal and external quality assurance). Participation in proficiency testing (MSZ EN ISO 17043:2010) is a must, where the results are evaluated by statistical methods as defined by the ISO 13528:2005 standard. Some aspects are summarized how to select appropriate laboratory services.]

Journal of Nursing Theory and Practice

[Value research of students in the patient care sector. Research carried out in a vocational secondary school]

KOVÁCSNÉ MELHER Marianna

[Aim of the study: Mapping out the value system, the professional motivation and the socio-cultural background of care provider students at the Zsuzsanna Kossuth Vocational Secondary School Sample and methods: Descriptive type research, number of elements 169 (n=169). The data was synthesized with Microsoft Office Excel 2007. Results: Taking into consideration the influence of the parents’ educational and professional background it can be stated that the parents’s influence gains control of their children’s school choice. In every analyzed group students are backed by strong family support. Regarding their career choice most students were motivated by the desire to help people. Graduate students demonstrate a more consistent career choice than younger students. The most important values of the care provider career proved to be: professional knowledge, know-how, responsibility and precision. An increase in career values related to age has not been demonstrated. Conclusions: It is very important to know the students’s value system because the values gained in the family and at school play a determining role in the care providers’s job. ]

Clinical Neuroscience

[Apoptosis in focal brain ischaemia]

ZÁDOR Zsolt, LACZA Zsombor, BENYÓ Zoltán, HARKÁNY Tibor, HORTOBÁGYI Tibor

[Ischaemic stroke is one of the major causes of death and disability in the developed world. It is caused by focal impairment of cerebral blood flow. The subsequent ischaemic cell death is predominantly necrotic in nature. However, a therapeutically important characteristic is the delayed apoptotic cell demise in the border zone of the primary lesion core. Apoptosis is one of the most intensively studied field of current medical and biological research. The better understanding of its mechanism may provide novel and more effective ways of therapy in a wide range of diseases including ischemic stroke. The salient neurological features of focal brain ischaemia and the morphological signs of apoptotic and necrotic cell death are summarized. The mechanism of apoptosis is discussed. It is divided into an early genetic phase of decisionmaking followed by a cellular execution phase. The characteristics of the early shift in the finely tuned balance of proand antiapoptotic genes and their protein products, which is preceded by an inbalance in intracellular ionized calcium homeostasis, energy depletion and mitochondrial dysfunction is discussed. The crucial role of caspases in apoptosis is emphasized. The three possible pathways during the execution phase is described: the intrinsic- and extrinsic caspase activation cascade and the caspase-independent intracellular signal transduction route. The molecular mechanism of neural cell membrane damage in the execution phase is discussed and some examples of altered protein synthesis also known as message-selection are given. The important role of late reperfusion in the execution phase is emphasized. The possible targets of antiapoptotic therapeutic approaches and the results of experimental studies are presented as well as the perspectives of their use in human clinical care.]

Hungarian Radiology

[Diagnostic difficulties of pancreatic rupture caused by blunt abdominal trauma]

WENINGER Csaba, ROSTÁS Tamás, MORÓ Zsuzsanna, GERSEI Emma

[INTRODUCTION - The aim of this study was to analyze the radiological observations of four cases of pancreatic fracture caused by blunt abdominal trauma. PATIENTS AND METHOD - The authors diagnosed pancreatic transection in four patient during a 4-year period. The patients were examined with spiral CT. Two children suffered pancreatic injury caused by blunt abdominal trauma (7,5 and 13 years old) and two adult men (40 and 35 years old). RESULTS - The abdominal ultrasound examination was not diagnostic regarding to pancreatic injury, but depicted free abdominal fluid and associated injuries of other organs. The pancreatic fracture was diagnosed only in one case at the first abdominal CT. The examiner failed to recognize the pancreatic transection in two cases at the initial CT. A pseudocyst was diagnosed by the examiner correctly in the 4th case, depicted earlier with US some weeks after the blunt abdominal trauma, but the pancreatic rupture was seen during reviewing of the CT scans, only. CONCLUSION - The recognition of pancreatic injury is difficult but very important, because it requires surgical intervention. In the literature, spiral CT considered as the best imaging technique in the evaluation of pancreatic injury. The radiologist has to think about the traumatic injury of pancreas also and know the signs of pancreatic fracture.]