Hungarian Radiology

[A true European radiologist - Interview with professor Gabriel Paul Krestin]

HARKÁNYI Zoltán

OCTOBER 20, 2004

Hungarian Radiology - 2004;78(05)

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Hungarian Radiology

[In vitro optimization of sequences applicable for the MR examination of the gastrointestinal tract with respect to certain contrast materials]

BABOS Magor, PALKÓ András, KARDOS Lilla, CSERNAY László

[PURPOSE - Optimization of gradient-echo and spin-echo sequences in order to visualize oral contrast media for magnetic resonance imaging (MRI) of the small bowel using a 1-T unit. MATERIAL AND METHODS - Authors investigated the optimal appearance of four different potential oral contrast media (rosehip syrup, blackcurrant extract, iron(III)-desferrioxamine, cocoa) with different spin-echo and gradientecho sequences using a simple plastic model. They were searching the optimal solution by changing the parameters of the chosen sequences keeping an eye in every case on the signal-to-noise ratio, the contrast, the resolution, the artifacts and the signal intensity of the contrast materials. RESULTS - The gradient-echo sequences are suitable for imaging of the small bowel. Too short echo time should be avoided because of the increased formation of artifacts. A lot of artifacts can be eliminated using fat saturation. T2*- weighted gradient-echo sequences provide good appearance for the cocoa drink, as well as the three-dimensional gradient-echo sequence. The use of sequential gradientecho acquisition methods is advisable only in non-cooperating patients, because of their low signal-to-noise ratio. The iron(III)-desferrioxamine solution, the rosehip syrup and the blackcurrant extract are potential positive contrast agents on T1-weighted sequences. On the single-shot fast spin-echo (SSFSE) sequence the rosehip syrup and the blackcurrant extract appear as negative contrast materials. CONCLUSIONS - Authors could select and optimize the sequences suitable for each contrast material and effective in small bowel MRI. The substances used in their experimental model are not harmful for humans when administered orally, so determination of additives is the only problem remained before their use in the clinical practice.]

Hungarian Radiology

[Pelvic computed tomography in staging of prostate cancer before surgery]

BERCZI Csaba, TÓTH György, VARGA Attila, FLASKÓ Tibor, KOLLÁR József, TÓTH Csaba

[PURPOSE - The aim of the study was to measure the sensitivity and specificity of computed tomography for local staging in patients underwent radical perineal prostatectomy. PATIENTS AND METHODS - 160 patients were involved in the study. Rectal digital examination, measurement of prostate specific antigen, prostate biopsy, CT, ultrasound, chest X-ray examination and bone scintigraphy were performed in every case before radical prostatectomy. RESULTS - The average preoperative prostate specific antigen concentration was 15.8 ng/ml before surgery. The average Gleason score of biopsies was 3.19. CT showed extraprostatic infiltration in 14 patients (pericapsular invasion n: 6, seminal vesicula n: 3, bladder infiltration n: 5, lymph node metastasis n: 2). The histological examination proved extraprostatic invasion of the tumour in 35 cases (pericapsular invasion n: 35, seminal vesicula n: 25, bladder infiltration n: 5). The cancer was localized in the prostate in 125 patients. Sensitivity and specificity of CT for pericapsular invasion were 14% and 98%, for infiltration of seminal vesicula 12% and 100%, and for bladder infiltration 20% and 97%. There was not a significant difference between the prostate specific antigen values (p=0.94) in cases when the tumour was confined to the prostate and when the cancer showed extraprostatic infiltration. There was significant difference between the Gleason score values between the two groups (p=0.008). CONCLUSION - The sensitivity of CT for local spread of prostate cancer is very low, thus CT is not a suitable method for the local staging before surgery.]

Hungarian Radiology

[PACS-seeing in Nancy - Study-tour, September, 2004]

FORRAI Gábor, BARTA Miklós

Hungarian Radiology

[Radiation protection belongs to patient’s right]

SZÁNTÓ Dezső

Hungarian Radiology

[Breast cancer screening in Hold street started twenty five years ago]

GÖBLYÖS Péter, TANKA Ida, GRÉGER Judit

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[Background and purpose - Data on disease burden of multiple sclerosis from Eastern-Central Europe are very limited. Our aim was to explore the quality of life, resource utilisation and costs of ambulating patients with multiple sclerosis in Hungary. Methods - Cross-sectional questionnaire survey was performed in two outpatient neurology centres in 2009. Clinical history, health care utilisation in the past 12 months were surveyed, the Expanded Disability Status Scale and the EQ-5D questionnaires were applied. Cost calculation was conducted from the societal perspective. Results - Sixty-eight patients (female 70.6%) aged 38.0 (SD 9.1) with disease duration of 7.8 (SD 6.7) years were involved. Fifty-five (80.9%) had relapsing-remitting form and 52 (76.5%) were taking immunomodulatory drug. The average scores were: Expanded Disability Status Scale 1.9 (SD 1.7), EQ-5D 0.67 (SD 0.28). Mean total cost amounted to 10 902 Euros/patient/year (direct medical 67%, direct nonmedical 13%, indirect costs 20%). Drugs, disability pension and informal care were the highest cost items. Costs of mild (Expanded Disability Status Scale 0-3.5) and moderate (Expanded Disability Status Scale 4.0-6.5) disease were 9 218 and 17 634 Euros/patient/year respectively (p<0.01), that is lower than results from Western European countries. Conclusion - Our study provides current inputs for policy making and contributes to understanding variation of costof- illness of multiple sclerosis in Europe.]

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The prevalence of sarcopenia and dynapenia according to stage among Alzheimer-type dementia patients

YAZAR Tamer, YAZAR Olgun Hülya

Aim - In this study, the aim was to identify the prevalence of sarcopenia and dynapenia according to disease stage among Alzheimer-type dementia (AD) patients and collect data to suggest precautions related to reducing the disease load. Method - The study was completed with 127 patients separated into stages according to Clinical Dementia Rating Scale (CDR) criteria and 279 healthy volunteers aged 18-39 years and 70-80 years abiding by the exclusion criteria who agreed to participate in the research. Our prospective and cross-sectional study applied the CDR and mini mental test (MMSE) to patients with disorder in more than one cognitive area and possible AD diagnosis according to NINCDS-ADRDA (National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer’s Disease and Related Disorders Association) diagnostic criteria. The patient and control groups had skeletal muscle mass index (SMMI), muscle strength and physical performance assessed with sarcopenia diagnosis according to European Working Group on Sarcopenia in Older People (EWGSOP) diagnostic criteria. Results - In our study, in parallel with the increase in disease stage of AD patients, the prevalence of sarcopenia (led by severe sarcopenia) and dynapenia was higher compared to a control group of similar age. Conclusion - In chronic, progressive diseases, like AD, identification of changes in parameters, like muscle mass and strength and reductions in physical performance in the early period, is important for identification and to take precautions in the initial stages considering the limitations of the preventive effects of treatment applied after diagnosis of AD.