Clinical Neuroscience

[Traumatic aneurysm in the cortical branch of the middle cerebral artery]

KÖVÉR Ferenc1, MÉREI F. Tibor1, GELLÉT Marianna1

AUGUST 01, 1985

Clinical Neuroscience - 1985;38(08)

[The course of a female patient with a traumatic aneurysm of the cortical branch of the cerebral medial artery two months after a covered skull injury with a lineal fracture of the lamina vitrea is described. It highlights the importance of performing angiography in cases where the cause of deterioration following trauma is not detected by CT scanning. It provides data to identify the morphological features of traumatic intracranial aneurysms by histological processing of the aneurysm. ]

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  1. Pécsi Orvostudományi Egyetem Idegsebészeti Klinikája és a Tatabányai Megyei Kórház-Rendelőintézet Idegosztálya

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[Authors summarize the key principles of diagnosis, genetics and genetic counselling of schizophrenic psychosis for practicing psychiatrists and the medical geneticist from the perspective of genetic counselling. With regard to the strategy of genetic counseling, the importance and simultaneous consideration of socio-cultural, socio-psychological factors and the family emotional-atmosphere are emphasized, in addition to nosological aspects. The special situation of schizophrenic (and psychiatric) patients and their families makes it advisable to set up a separate psychiatric genetic counselor. ]

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[The authors performed HLA typing in 5 families with tuberous sclerosis (ST), demonstrating a significantly higher prevalence of HLA-A w31 antigen, without involvement of the B an antigen group. An autosomal dominant origin was confirmed in 4 families and a first gene mutation origin in 1 family, based on UV light examination of the outer skin of the family members, with detectable fluorescence of depigmented spots. Of 6 cases of neurofibromatosis (Nf), 4 were forme fruste forms, the inheritance pattern was autosomal dominant in 4 families and first gene mutation in 1 family was proven. The authors also discuss the diagnostic value of computed tomography in the above pathologies. ]

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[For more than three years in a psychiatric unit, they have managed to engage 6 of the 36 paranoid psychotics referred to them for an hour a week, who need extra help. At his request, 2 sensitive neurotics with neurotic neuroses were linked to the group. The group, which had been operating under the same conditions as before, was characterised by the emotional and experiential involvement of the therapists, treating the patients as equals and observing the group process passively and impartially. The results of such complementary treatment are good, although miracles are not expected. As a new finding compared to the scarce literature worldwide on outpatient group psychotherapy with psychotics, we found that disengagement in such groups is difficult and requires even greater empathy and more developed self-awareness of the therapists than the group design. ]

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[The authors determined the total activity of lactic dehydrogenase (LDH) and malic dehydrogenase (MDH) per wet weight and the percentage distribution of LDH isoenzymes in muscle samples taken during thymectomy from the sternothyroid muscle of 62 patients with myasthenia gravis, and calculated the MDH/LDH ratio and the percentage of H and M subunits. In comparing their results with clinical data, they found that significant decreases in the percentage of LDH; isoenzyme and M subunit, and trend-like decreases in total LDH activity and increases in the MDH/LDH ratio per case, correlated with the degree of histopathologically detected ischemia in the samples and the frequency of clinically manifest ischemia and respiratory crises in the history. In their opinion, the biochemical abnormalities observed in the damaged muscle samples indicate a decrease in anaerobic glycolysis in the form of myasthenia gravis with myasthenia gravis associated with muscle atrophy. The histological examination revealed similar but milder abnormalities in intact muscle samples, in addition to an early biochemical sign of muscle destruction, raising the possibility of a possible biochemical level adaptive compensatory mechanism in myasthenic muscle. This study may be a useful adjunct to other known methods for the early detection of muscle wasting as a complication of myasthenia gravis. ]

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