Clinical Neuroscience

[The problems of the psychoanalytical distinguishing between typical and atypical types of drunkenness]

HUSZÁR Ilona1, IRÁNYI Jenőné1

MAY 01, 1967

Clinical Neuroscience - 1967;20(05)

[In their communication, the authors deal with the differentiation of acute, typhoidal intoxication states from atypical (pathological) intoxication states, emphasising the sociological importance of the differentiation and defining the legal basis for the differentiation. The work of Nyirő on the subject is discussed in detail, followed by a discussion of the symptoms of atypical intoxication and their diagnostic significance. They also analyse all the external and internal factors that may play a role in the development of atypical drunkenness. It is considered possible to distinguish between the two forms of intoxication only by examining all the factors in each case in context, but it is stressed that a sharp dividing line cannot always be drawn. ]

AFFILIATIONS

  1. Budapesti Orvostudományi Egyetem Psychiatriai Klinikája

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Clinical Neuroscience

[Statistical processing of 15 years of ES material from the Psychiatric Clinic of the Budapest Medical University]

ORVOSI Kara

[In the struggle for the cure of mental illnesses, for the health of the human mind, one of the central issues was therapeutic optimism, therapeutic activitas. The sick person and society as a whole expect the best possible restitution from the doctor, and the doctor's duty as a practitioner is to take responsibility, to take the lead, to apply the most modern methods of treatment. ]

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[Schizophrenia or schizophrenias]

DRIETOMSZKY Jenő, BRUNECKER Györgyi

[In analysing the development of the concept of "schizophrenia", both in terms of its professional history and its theoretical basis, authors adopt Nyirő's position that "...we cannot speak of schizophrenia, only of schizophrenics..." In the sense of Sternberg's concept, they narrow down their position by stating that a nosological approach and Leonhardian taxonomy are essential requirements for a substantive answer to the question.]

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[Resuscitation and neuropsychiatric therapy experiences with electrostimulator]

FORNÁDI Ferenc, BARTOS Valéria, ZSOMBÓK György, KAFFKA Károly

[The authors describe their joint research with Nyirő on the therapeutic value of transcerebral electrostimulation. Their experience: 1. electrostimulation is essential not only in the treatment of respiratory paralysis following electrotrauma, but also in the prevention and treatment of certain complications of psychiatric so-called major somatic treatments; 2. it is also a new treatment option for hormone-refractory hypothalamic syndromes, such as amenorrhoea, using more mitigated current parameters. ]

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[The role of exogenous factors in psychiatric disorders ]

IVÁN László, TAKÁCS László, PETHŐ Bertalan

[Authors discuss the psychopathological significance of isolation or deprivation. They draw attention to these specific exogenous factors and stress the importance of a multidimensional approach in their interpretation. Using both the literature and their own clinical experience, they aim to outline certain conclusions on this topic. ]

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[Superstition and psychosis]

FORNÁDI Ferenc, VARGA Ervin, POHL Ödön

[The authors analyse the mystical and superstitious experiences of psychotic and neurotic patients and their interpretation in 5 cases. They relate the symptoms to environmental influences (childhood experiences, cultural and social influences). ]

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Fluoxetine use is associated with improved survival of patients with COVID-19 pneumonia: A retrospective case-control study

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We aimed to investigate the association between fluoxetine use and the survival of hospitalised coronavirus disease (COVID-19) pneumonia patients. This retrospective case-control study used data extracted from the medical records of adult patients hospitalised with moderate or severe COVID-19 pneumonia at the Uzsoki Teaching Hospital of the Semmelweis University in Budapest, Hungary between 17 March and 22 April 2021. As a part of standard medical treatment, patients received anti-COVID-19 therapies as favipiravir, remdesivir, baricitinib or a combination of these drugs; and 110 of them received 20 mg fluoxetine capsules once daily as an adjuvant medication. Multivariable logistic regression was used to evaluate the association between fluoxetine use and mortality. For excluding a fluoxetine-selection bias potentially influencing our results, we compared baseline prognostic markers in the two groups treated versus not treated with fluoxetine. Out of the 269 participants, 205 (76.2%) survived and 64 (23.8%) died between days 2 and 28 after hospitalisation. Greater age (OR [95% CI] 1.08 [1.05–1.11], p<0.001), radiographic severity based on chest X-ray (OR [95% CI] 2.03 [1.27–3.25], p=0.003) and higher score of shortened National Early Warning Score (sNEWS) (OR [95% CI] 1.20 [1.01-1.43], p=0.04) were associated with higher mortality. Fluoxetine use was associated with an important (70%) decrease of mortality (OR [95% CI] 0.33 [0.16–0.68], p=0.002) compared to the non-fluoxetine group. Age, gender, LDH, CRP, and D-dimer levels, sNEWS, Chest X-ray score did not show statistical difference between the fluoxetine and non-fluoxetine groups supporting the reliability of our finding. Provisional to confirmation in randomised controlled studies, fluoxetine may be a potent treatment increasing the survival for COVID-19 pneumonia.

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Late simultaneous carcinomatous meningitis, temporal bone infiltrating macro-metastasis and disseminated multi-organ micro-metastases presenting with mono-symptomatic vertigo – a clinico-pathological case reporT

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Clinical Neuroscience

[The role of sleep in the relational memory processes ]

CSÁBI Eszter, ZÁMBÓ Ágnes, PROKECZ Lídia

[A growing body of evidence suggests that sleep plays an essential role in the consolidation of different memory systems, but less is known about the beneficial effect of sleep on relational memory processes and the recognition of emotional facial expressions, however, it is a fundamental cognitive skill in human everyday life. Thus, the study aims to investigate the effect of timing of learning and the role of sleep in relational memory processes. 84 young adults (average age: 22.36 (SD: 3.22), 21 male/63 female) participated in our study, divided into two groups: evening group and morning group indicating the time of learning. We used the face-name task to measure relational memory and facial expression recognition. There were two sessions for both groups: the immediate testing phase and the delayed retesting phase, separated by 24 hours. 84 young adults (average age: 22.36 (SD: 3.22), 21 male/63 female) participated in our study, divided into two groups: evening group and morning group indicating the time of learning. We used the face-name task to measure relational memory and facial expression recognition. There were two sessions for both groups: the immediate testing phase and the delayed retesting phase, separated by 24 hours. Our results suggest that the timing of learning and sleep plays an important role in the stabilizing process of memory representation to resist against forgetting.]