Clinical Neuroscience

Surgery of vertebro-basilar aneurysms re-evaluated

VAJDA János1, NYÁRY István1, CZIRJÁK Sándor1, HORVÁTH Miklós1

MAY 20, 1994

Clinical Neuroscience - 1994;47(05-06)

It has long been a common view of the world's neurosurgical community that saccular aneurysms located at the junction of bilateral vertebral arteries where the basilar artery arises from (VB aneurysm) impose extreme diffuculties to their surgical repair. These difficulties have been agreed to be caused by the narrowest working space for dissecting and clipping the aneurysm, while structures around this particular location with their vital functional importance are most sensitive to retraction. The difficulties have been apparently amplified when the aneurysm had recently ruptured because of further limits in mobilizing aneurysm, vessels and attached surfaces. As the experiences of our aneurysm surgery team in the National Institute of Neurosurgery have increased, our attitude toward these lesions used to be called no-man’s-land aneurysms have gained more and more confidence and this is felt as the right time to report our results.


  1. National Institute of Neurosurgery, Budapest, Hungary



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Clinical Neuroscience

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Correlation of clinical and molecular genetic findings in malignant brain stem tumors

V. K. Ammon, U. Sure, DN Louis, V. Deimling A.

Brain stem gliomas are rare, predominantly pediatric tumours. Histologically, they are comparable to adult supratentorial astrocytomas. Most of the pediatric brain stem tumours were classified as low-grade astrocytoma (WHO II), anaplastic astrocytoma (WHO III) or glioblastoma multiforme (GBM, WHO IV). Survival of patients with malignant brain stem gliomas as WHO grade III and IV rarely exceeds more than two years. Recently developed molecular genetic techniques gave new insights in tumour biology. Oncogenes and tumour suppressor genes are genetic alterations which can cause tumorous transformation and furthermore malignant progression. Molecular genetic studies of malignant brain stem gliomas have rarely been investigated. Therefore, we set out to study 12 such tumours clinically and 2 by molecular biological methods.

Clinical Neuroscience

Simultaneous occurence of unilateral multiplex meningiomas and syringomyelia

BÜKI András, MÉSZÁROS István, KÖVÉR Ferenc, KASÓ Gábor

Long lasting intracranial hypertension is considered to be a major pathogenic factor of syringomyelia in patients with a Chiari malformation or posterior fossa tumor.

Clinical Neuroscience

Different autoregulatory responses in the cerebellar cortex, neocortex and subcortical gray matter of the rat to systemic hypo- and hypertension


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Clinical Neuroscience

Epidermoid tumours of the posterior fossa

K. Bálint, F. Slowik, M. Kordás, J. Juhász, J. Julow

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Clinical Neuroscience

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