Clinical Neuroscience

[Quantitative electromyography]

MECHLER Ferenc1, KAJTOR Ferenc1

SEPTEMBER 01, 1963

Clinical Neuroscience - 1963;16(09)

[It can be concluded that the operator of quantitative electromyography must have considerable neurological experience, must be able to determine in which cases electromyography is necessary and which muscles should be examined in a given case. However, there is no doubt that the objective diagnostic value of the quantitative method of electromyography is also greater, albeit more costly and more work than the older, non-quantitative routine method that is more commonly used. ]

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  1. Debreceni Orvostudományi Egyetem Ideg- és Elmeklinikája

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[Electroencephalographic studies in children with congenital vitium ]

RÁKOS György

[Electroencephalography was performed in 80 children with congenital vitium. Among 40 non-cyanotic, cardiac-compensated, clinically intact children with a clinically intact nervous system, only one with coarctation of the aortae was found to have an abnormality. Of 40 children with cyanotic congenital vitium, 13 were found to have cerebral lesions with eeg. No correlation was found between haematological data and eeg abnormality. A higher than average number of children with severe mental retardation and dyspnoea with sudden onset of hypoxia and cyanotic seizures with cyanotic seizures differed from the average. ]

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[In 1961, a village of 629 inhabitants consumed 500 000 HUF worth of alcoholic beverages. One individual spent more than 2 HUF per day for the total population and more than 6 HUF per day for the adult male population, which represents 12 and 36% of the total income per person respectively. 17 chronic alcoholics are from the better-off and more culturally demanding population of the village. The fight against alcoholism can be tackled by expanding cultural leisure activities, by creating a tax-efficient culture and by certain practical measures. ]

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[About the neurological causes of difficulty passing urine]

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[Some authors recognise a disease in which neither a neurological cause nor a local cause (inflammation of the sphincter or bladder neck or mechanical obstruction to urine emptying) can be identified, but urine emptying is probably obstructed by an overweight of the orifice intimal muscles. This is suggested by the recognition that these conditions can also be resolved by resection of the bladder neck.]

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[Cerebrospinal fluid hypotension associated with vaso-anoxic cerebral damage]

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[The authors present the case of a 47-year-old male patient who developed aliquorrhoea and severe apallium syndrome in the setting of fever (presumably influenza); the disease was cured without residual symptoms after antibiotic treatment and intrathecal and parenteral fluid therapy. Based on analysis of the clinical data, it is considered likely that both the aliquorrhoea and the neurological symptoms were the consequence of a disturbance of the intracranial circulation. In their case, the authors put forward their hypothesis that the pathomechanism of CSF hypotensive syndromes is due to circulatory dysfunction and secondary reflexes induced by a decrease in CSF pressure, which feed back to the cerebral and plexus circulation.]

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Atypical presentation of late-onset Sandhoff disease: a case report

SALAMON András , SZPISJAK László , ZÁDORI Dénes, LÉNÁRT István, MARÓTI Zoltán, KALMÁR Tibor , BRIERLEY M. H. Charlotte, DEEGAN B. Patrick , KLIVÉNYI Péter

Sandhoff disease is a rare type of hereditary (autosomal recessive) GM2-gangliosidosis, which is caused by mutation of the HEXB gene. Disruption of the β subunit of the hexosaminidase (Hex) enzyme affects the function of both the Hex-A and Hex-B isoforms. The severity and the age of onset of the disease (infantile or classic; juvenile; adult) depends on the residual activity of the enzyme. The late-onset form is characterized by diverse symptomatology, comprising motor neuron disease, ataxia, tremor, dystonia, psychiatric symptoms and neuropathy. A 36-year-old female patient has been presenting progressive, symmetrical lower limb weakness for 9 years. Detailed neurological examination revealed mild symmetrical weakness in the hip flexors without the involvement of other muscle groups. The patellar reflex was decreased on both sides. Laboratory tests showed no relevant alteration and routine electroencephalography and brain MRI were normal. Nerve conduction studies and electromyography revealed alterations corresponding to sensory neuropathy. Muscle biopsy demonstrated signs of mild neurogenic lesion. Her younger brother (32-year-old) was observed with similar symptoms. Detailed genetic study detected a known pathogenic missense mutation and a 15,088 base pair long known pathogenic deletion in the HEXB gene (NM_000521.4:c.1417G>A; NM_000521:c.-376-5836_669+1473del; double heterozygous state). Segregation analysis and hexosaminidase enzyme assay of the family further confirmed the diagnosis of late-onset Sandhoff disease. The purpose of this case report is to draw attention to the significance of late-onset Sandhoff disease amongst disorders presenting with proximal predominant symmetric lower limb muscle weakness in adulthood.

Journal of Nursing Theory and Practice

[Assessing Nurses’ Knowledge of Surgical Wound Care, Complications and Knowledge of Bandages]

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[Aim of our research was to assess the knowledge of nurses working in surgical departments about surgical wound treatment, phases of wound healing, its complications, and intelligent bandages. Our quantitative, cross-sectional, descriptive examination was carried out in a hospital in Transdanubia with non-random, expert sampling and a self-made questionnaire. Our target group was nurses working in the surgical departments of the hospital (N=85). During the data analysis, the descriptive statistical methods of MS Office Excel 2016 software were calculated: mean, standard deviation, frequency. A χ2-test was used to examine the relationship between variables (p <0.05). Knowledge of bandages was not affected by educational attainment (p>0.05). Those who perform wound care in their daily work have more knowledge about the wound treatment sequence of the wounds that are primarily healing, as well as about intelligent dressings (p<0.1). For the classes, there was a significance for the recognition of complicated wounds, knowledge of the benefit of the absorbable suture and the use of analgesic procedures (p<0.001). In the interests of patient safety, nurses’ knowledge of wound treatment needs to be continuously improved. It is necessary to provide an accessible source of information and further training.]

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Journal of Nursing Theory and Practice

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