Clinical Neuroscience

[Maladies infectieuses extraneurales du système nerveux complications]

KÖRNYEY István1

JANUARY 01, 1968

Clinical Neuroscience - 1968;21(01)

[Overview of neurological complications of common infectious diseases it is most useful to start from the following classification of encephalomyelitis based on its pathophysiological features, although only certain types are associated with our thymus: 1. meningo-encephalitis; 2. metastatic nodular encephalitis (abscess); 3. diffuse encephalitis, mainly involving the cerebral cortex; 4. polioencephalomyelitis, with pre-dilection areas of the brainstem disease of the prefrontal lobes of the brain; 5. panencephalitis; 6. leukoencephalitis.]

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  1. Pécsi Orvostudományi Egyetem Ideg-és Elmeklinika

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Clinical Neuroscience

[Pemphigus cases with lesions found in the spinal ganglia ]

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Observations upon the So-colled Idiots Savants

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In drawing the foregoing generalisations it is necessary to realise their limitations. We must agree with the conclusions arrived at by Mitchell, who recognised at least three psychological categories: (1) the “calculating prodigies — who may be persons of inferior intellectual calibre and who rely upon ingenious shortcuts; (2) arithmetical prodigies like Colburn, and Dase, with a moderately well developed knowledge of arithmetic; and (3) mathematical geniuses, such as the elder Bidder. These are endowed with exceptional abilities, and their knowledge of pure mathematics is profound.

Clinical Neuroscience

Thorium granulomas in the brain

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Thorotrast was used in 1936 and 1937 to demonstrate the lesions of prefrontal lobotomy. Four patients came to autopsy after 10-22 years, and in each, one or more thorium granulomas were found. These masses ranged from 6 X 8 mm to 8X12 mm in size, were composed of hyaline material enclosed by a thick capsule of mixed connective and glia tissue, and surrounded in part by large phagocytes filled with thorium dioxide particles. Dense connective tissue developed in sulci where thorotrast escaped into the subarachnoid spaces, and marked gliosis with desquamation of the ependyma occurred when it entered the ventricles. The phagocytes in the cases with longer survival often showed vacant cavities where the nuclei should have been. Neurons in the vicinity showed no obvious lesions. The material was described as containing "a very strong thorium source.” It is believed that the alpha particles given off by the thorium are responsible for the formation of the granulomas and, after many years, for the death of the phagocytes. Thorium can safely be used in the brain only for the demonstration of cysts and abscesses which can then be completely removed. A case of such employment was described by Lehoczky in 1939.

Clinical Neuroscience

Télangiectasies de la moelle dorsale révélées à l'âge de 75 ans par une myelopathie transverse, avec une digression sur l'atrophie spinale segmentaire

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L'observation que nous rapportons tire son intêret de la révélation extrêmement tardive (75 ans) d'un angiome de la moelle de type capillaire, resté jusque là cliniquement muet. Elle illustre la longue latence possible des mal formations vasculaires de la moelle, et elle montre qu'il faut toujours penser à cette étiologie devant une affection médullaire dont la cause nous échappe.

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Clinical Neuroscience

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Clinical Neuroscience

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Clinical Neuroscience

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