Clinical Neuroscience

[Histamine content of various nerve elements]

LISSÁK Kálmán1, SZEKERES Vera1

SEPTEMBER 09, 1950

Clinical Neuroscience - 1950;3(03)

[In addition to the well-defined cholinergic and adrenergic nerves, histaminergic nerves have recently been distinguished. Lewis and Marvin were the first to show that a building material (H-matter) is released in the skin when the back radicals are stimulated. Ungar and Zerling believe that vasodilator nerve fibres would belong to the histaminergic group, because the excitatory effect occurs by histamine release when spinal dorsal roots are stimulated.]

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Clinical Neuroscience

Atypical presentation of late-onset Sandhoff disease: a case report

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Clinical Neuroscience

REM sleep, REM parasomnias, REM sleep behaviour disorder

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We review the literature on REM parasomnias, and their the underlying mechanisms. Several REM parasomnias are consistent with sleep dissociations, where certain elements of the REM sleep pattern emerge in an inadequate time (sleep paralysis, hypnagogic hallucinations and cataplexy) or are absent/partial in their normal REM sleep time (REM sleep without atonia, underlying REM sleep behavior disorder). The rest of REM parasomnias (sleep related painful erection, catathrenia) may have other still unclear mechanisms. REM parasomnias deserve attention, because in addition to disturbing sleep and causing injuries, they may shed light on REM sleep functions as well as the heterogeneous etiologies of parasomnias. One of them, REM sleep behavior disorder has special importance as a warning sign of evolving neurodegenerative conditions mainly synucleinopathies (some cases synucleinopathies themselves) and it is a model parasomnia revealing that parasomnias may have by autoimmune, iatrogenic and even psychosomatic etiologies.