Clinical Neuroscience

[Cronicle]

KOVÁCS László, TAKÁCS László, HUSZÁR Ilona

JUNE 01, 1966

Clinical Neuroscience - 1966;19(06)

[The author reports on the presentations at the Pavlov Neuro-Mental Group meeting.]

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Clinical Neuroscience

[Experimental porphyrism and its relevance to human disease ]

LEHOCZKY Tibor, SÓS József, SELMECY László, HALASY Margit

[Authors have induced experimental porphyria in white rats. 13 animals with allyl isopropyl acetamide carbamide (Sedormid), 6 with griseofulvin (Likuden). This is the first successful experiment in the rat, having only been done in mice. The combined results of the two experiments: in all cases (19) very severe lesions were observed in the spinal cord and cortical neurons; spongiotic degeneration was observed in the white matter of the spinal cord of 16 animals, in the hippocampus and brainstem of 4 animals; in 2 cases demyelination was seen in the Burdach tracts of the spinal cord; finally, small haemorrhages were observed in the spinal grey horns of 3 animals. These experiments have demonstrated that the clinical signs described in experimental porphyria have a solid neurological basis. Their results are consistent with the neuropathological lesions reported in human disease, and thus their experiments are experimental evidence of human clinicopathological findings. ]

Clinical Neuroscience

[Evaluation of the treatment of depression (comparative, retrospective analysis)]

VARGA Ervin, JULES Angst, MICHAEL Shpherd

[We compared 3 common somatic treatments for depressive disorders [ES, Imipramine, Monoamine Oxidase Inhibitors (MAOIs)].]

Clinical Neuroscience

[Lethal mumps encephalitis in a six-year-old child]

NAGY József, JURÁSZ Gabriella

[The authors describe a case of mumpssencephalitis with lethal outcome in a 6-year-old child, together with detailed brain histology findings. The clinical picture was characterized by the absence of meningeal symptoms, the predominance of disturbance of consciousness and the late onset of neurological laesio. The parainfectious type of encephalitis is localized mainly in the immediate vicinity of ventricles III and IV, which explains the peculiarities of the clinical course. The parotid and submandibular salivary glands and interstitial inflammation of the testis are sub-symptoms of mumps and also prove the mumps origin of the encephalitis. ]

Clinical Neuroscience

[Congenital absence of cerebellum]

VERES János, BODÁNSZKY Hedvig

[In conclusion, it is a metameric developmental disorder, of which cerebellar agenesis is an extremely rare feature. Among the factors leading to intrauterine harm, heredity, X-ray, radium harm, mechanical impact and viral diseases cannot be proven. ]

Clinical Neuroscience

[Addendum to the pathology of symptomatic narcolepsy]

POHL Ödön

[The author describes the case of a 52-year-old man who had a history of typhoid narcoleptic seizures with hypnagogic hallucinations for a year. The pathological findings showed a picture of an abortive, indeterminate polyoencephalitis with the focus of the inflammatory lesion located in the area paramediana posterior to the grey matter of the periventricular grey matter of the thalamus.]

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