Clinical Neuroscience

[About testing procedures in myasthenia gravis]

SZOBOR Albert1

DECEMBER 01, 1966

Clinical Neuroscience - 1966;19(12)

[The principles and purpose of diagnostic procedures in myasthenia gravis. Description of the tests: 1. Physical tests for myasthenia gravis - 2. Electrical testing procedures - 3. Pharmacological tests - 4. Combination tests. - 5. Other tests. - Personal experience based on the observations of 91 patients with myasthenia. Description of own procedures: ergometric test, Jolly+Tensilon combination test and relaxation test.]


  1. Budapest XIII. ker. Róbert Károly krt. Kórháza Organicus Idegosztály



Further articles in this publication

Clinical Neuroscience

[Data on carotid circulatory dysfunction (Preliminary Communication)]


[Since 1962, the authors have reported 12 cases of carotid thrombosis and 15 cases of carotid insufficiency without thrombosis. They consider it appropriate to discuss carotid circulatory disorders by syndrome (carotid insufficiency syndrome). Among the clinical signs, great importance is attached to the auditory sensation over the carotid artery and local tenderness to pressure. Among the instrumental investigations, the carotid pulse curve is a feature in cases of insufficientia without thrombosis, and in cases of internal carotid artery thrombosis, it may be a useful diagnostic tool in addition to carotid angiography. ]

Clinical Neuroscience

[Sociometric assessment of inpatient mental health patients]

SZABÓ Endre, BOHÁCS Elemér, MURAKÖZY Ferencné

[The authors examined 100 patients to identify familial, social and cultural factors that may play a significant role in the development and course of psychosis. They stress the importance of assessing environmental influences in patients.]

Clinical Neuroscience

[Neurological complications associated with chondrodystrophy]


[After a summary of the neurological complications associated with osteochondrodystrophy, we described our own similar case. Symptoms of partial spinal cord lacunar lesion were present after spinal trauma, and an anterolisthesis of the C vertebra with significant narrowing of the spinal canal was detected by CT scan. Vasodilator treatment was performed to improve collateral circulation while maintaining tensio-level. An improvement of symptoms, unchanged for 10 years and worsening in recent months, was observed. In the case of chondrodystrophic neurological complications, orthopaedic stretching treatment may be attempted. If unsuccessful, extensive decompressive laminectomy may be recommended, especially in cases of a herniated disc or sudden onset of spinal cord injury. In cases not amenable to surgical treatment, vasodilatation and physiotherapy may be effective in maintaining arterial blood pressure at an appropriate level.]

All articles in the issue

Related contents

Clinical Neuroscience

[The role of sleep in the relational memory processes ]

CSÁBI Eszter, ZÁMBÓ Ágnes, PROKECZ Lídia

[A growing body of evidence suggests that sleep plays an essential role in the consolidation of different memory systems, but less is known about the beneficial effect of sleep on relational memory processes and the recognition of emotional facial expressions, however, it is a fundamental cognitive skill in human everyday life. Thus, the study aims to investigate the effect of timing of learning and the role of sleep in relational memory processes. 84 young adults (average age: 22.36 (SD: 3.22), 21 male/63 female) participated in our study, divided into two groups: evening group and morning group indicating the time of learning. We used the face-name task to measure relational memory and facial expression recognition. There were two sessions for both groups: the immediate testing phase and the delayed retesting phase, separated by 24 hours. 84 young adults (average age: 22.36 (SD: 3.22), 21 male/63 female) participated in our study, divided into two groups: evening group and morning group indicating the time of learning. We used the face-name task to measure relational memory and facial expression recognition. There were two sessions for both groups: the immediate testing phase and the delayed retesting phase, separated by 24 hours. Our results suggest that the timing of learning and sleep plays an important role in the stabilizing process of memory representation to resist against forgetting.]

Clinical Neuroscience

Electrophysiological investigation for autonomic dysfunction in patients with myasthenia gravis: A prospective study


Myasthenia gravis (MG) is an autoimmune disorder of neuromuscular transmission. Autonomic dysfunction is not a commonly known association with MG. We conducted this study to evaluate autonomic functions in MG & subgroups and to investigate the effects of acetylcholinesterase inhibitors. This study comprised 30 autoimmune MG patients and 30 healthy volunteers. Autonomic tests including sympathetic skin response (SSR) and R-R interval variation analysis (RRIV) was carried out. The tests were performed two times for patients who were under acetylcholinesterase inhibitors during the current assessment. The RRIV rise during hyperventilation was better (p=0.006) and Valsalva ratio (p=0.039) was lower in control group. The SSR amplitudes were lower thereafter drug intake (p=0.030). As much as time went by after drug administration prolonged SSR latencies were obtained (p=0.043).Valsalva ratio was lower in the AchR antibody negative group (p=0.033). The findings showed that both ocular/generalized MG patients have a subclinical parasympathetic abnormality prominent in the AchR antibody negative group and pyridostigmine has a peripheral sympathetic cholinergic noncumulative effect.

Lege Artis Medicinae

[Diagnosis and treatment of microvascular coronary heart disease. Specialities of conditions in Hungary]


[Invasive investigations show that in two-thirds of patients the myocardial ischaemia persists without obstructive coronary disease and any other heart conditions (INOCA). The underlying cause may be microvascular dysfunction (CMD) with consecutive microvascular coronary disease (MVD) and microvascular or epicardial vasospastic angina (MVA). The modern practice of clinical cardiology while using the developed non-invasive cardiac imaging permits exact measuring of the coronary flow with its characteristic indices. All of these improve the diagnosing of CMD-induced myocardial ischemia and provide opportunity to determine primary MVD cases. Since the recognition and treatment of MVD is significantly underrep­resented in the Hungarian medical care, the primary stable microvascular angina (MVA) is described in detail below with its modern invasive and non-invasive differential diagnosis and treatment, concerning especially its frequency provoked by high blood pressure and female coronary heart diseases. There are highlighted all recommended diagnostic procedures available under domestic conditions.]

Lege Artis Medicinae

[Covid-19 – testing the reality]

SVÉD Tamás

Journal of Nursing Theory and Practice

[Operational Efficiency Investigation from APN Perioperative Perspective]


[In the healthcare system operating theatres have to put great emphasis on quality work, patient safety and efficiency as well, and to achieve this, optimal utilization of theatres is extremely important. The results of researches in this topic in Hungarian and international literature draw attention to a lot of aspects. The study of perioperative periods, and the evaluation of the analysed processes show that theatres could be operated more effectively. As a result of this, more operations could be carried out and waiting time would also reduce. In order to increase the efficiency of the processes, APNs can play a prominent role at several points. According to the experience, the number of people using health care and the number of people waiting for surgery is increasing, which is further increased by the development of the ongoing SARS-CoV-2 (COVID-19) epidemic. Thereby, patients are not satisfied with the service. The work of APNs would also help increasing the contentment of patients during the operation procedures. Taking advantage of the multifunctional role of the nurse due to her knowledge and training, she actively participates in the operation, in the smooth running of the scheduled daily surgical program and contributes to the reduction of the number of missed, planned surgeries.]