Clinical Neuroscience

[About CSF plasma cells]

PÉTER Ágnes1

NOVEMBER 01, 1966

Clinical Neuroscience - 1966;19(11)

[ The author analyses the morphological and functional aspects of plasma cells detected in meningograms of 60 cases with inflammatory diseases of the central nervous system. Among the shape variants of the plasma cells, he isolated immature cell types that appeared in the cerebrospinal fluid. The young cell shapes of the CSF plasmocytes suggest a leptomeningeal origin of CSF plasma cells. The author found plasmocytic cytological reactions in the CSF of two patients, an accumulation of blast-type cells, secret-vacuolum-like lesions in the plasma cells and highly elevated gamma-globulin values. It raises the possibility that the plasma cells detected in CSF are immunoreactive and play a role in the production of CSF antibodies.Analysis of meningograms from 30 panencephalitic patients and CSF protein spectra from 18 cases revealed that leptomeningeal plasma cells were mainly involved in the production of CSF antibodies. s migrating gamma fractions. ]

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  1. Budapesti Orvostudományi Egyetem Neurologiai Klinikája

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