Clinical Neuroscience

[99 M TC HMPAO SPECT in children with intractable epilepsy]

NEUWIRTH Magdolna1, BORBÉLY Katalin2, KOPCSÁNYI Zsuzsanna3

NOVEMBER 20, 1997

Clinical Neuroscience - 1997;50(11-12)

[We examined the role of HMPAO SPECT examinations in presurgical evaluation of children with intractable partial epilepsy. SPECT studies (ictal, interictal) were performed on 31 children aged 1-18 years. The focus was restricted in 18 cases and extensive, ie, a whole hemisphere or some lobes, in 4 cases. SPECT indicated pathological changes in the relevant areas in 15 of 18 cases, but in 9 children with temporal epilepsy in all. The focus was extensive in 4 cases, e.g. in 3 children with Rasmussen syndrome. SPECT was pathologic in all of them when MRI did not yet show hemiatrophy of the brain. In 3 cases of partial epilepsy MRI did not demonstrate lesion, the focus was not well-defined by EEG, in contrast to SPECT. Thus it can be stated that SPECT provides valuable information on presurgical evaluation in children with intractable partial epilepsy.]

AFFILIATIONS

  1. Magyarországi Református Egyház Bethesda Gyermekkórháza
  2. Országos Idegsebészeti Tudományos Intézet
  3. Nemzetközi Egészségügyi Központ SPECT Laboratóriuma, Budapest

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