Clinical Neuroscience - 1952;5(02)

Clinical Neuroscience

JULY 29, 1952

[A new version of Jacod's syndrome]

MARIA Filipowicz

[Brain symptoms in nasopharyngeal tumours were observed as early as the second half of the 19th century. Observations on the frequency of certain brain lesions have been supplemented by descriptions of the pathways by which nasopharyngeal tumours penetrate the inside of the skull. For some time there were two opposing views on the origin and development of tumours. According to some authors, the tumour originates either from the nasopharynx or from the connective tissue of the skull base, and thus invades the skull from the outside, destroying the cranial nerves in its path. Others have argued that, on the contrary, elements within the skull are the starting point of the tumour, and that the process in the nasopharynx is independent or has been considered as a tumour metastasis from the inside of the skull to the outside. Doubts in this respect have only been dispelled by detailed study. It was found that in the majority of cases the nasopharyngeal space was the starting point. ]

Clinical Neuroscience

JULY 29, 1952

[Schizophrenia in childhood]

LÓRÁND S. Blanka

[According to the prevailing psychiatric view, schizophrenia is rare in childhood, and some authors, such as Vogt and Weichbrodt, have denied that it occurs before adolescence. However, a critical review of the older literature on childhood psychosis leads to the conclusion that it is not so much the rarity of childhood schizophrenia as its recognition and correct pathology: in the older descriptions, we often find images of childhood schizophrenia that are typified by the current understanding. ]

Clinical Neuroscience

JULY 29, 1952

[Data for the pathogenesis of morphinismus]

GARTNER Pál, KELEMEN Endre

[Since December 1950, authors have performed morphine withdrawal treatment on 32 morphine users referred from the KEKSZ. Their procedure is as follows: morphine is withdrawn immediately. On the first day of withdrawal, the patient receives 0.1-0.1 ccm of 2% morphine intracutaneously into the flexor aspect of both forearms, for a total of 4 mg. The same is given for the next 3 days. The fifth day is a break. On the sixth and seventh days he receives the same again. In addition: on days 1-3-6, another 3-5-10 ccm of foreign group blood is given intravenously. If there is an obstacle to hetero-blood injection, 10 ccm Resactor is given intramuscularly instead. This procedure is used to minimise withdrawal symptoms, and mood correctors are rarely needed. Patients usually leave on day 10 with no symptoms or complaints. The pathogenesis of morphinism is thought to be essentially immunobiological. They consider their new withdrawal treatment to be intracutaneous desensitisation and attribute the success of the treatment to the reduction in tolerance induced by the binding of morphine antibodies. Hetero-blood or Resactor injections mobilise antibodies through their effect on the RES system, which enhances the efficacy of the treatment. Treatment does not resolve the issue of relapse. ]

Clinical Neuroscience

JULY 29, 1952

[Fundus examinations in connection with electrohock]

KLIMES Károly, ERŐSS Sándor

[The introduction and use of cumulative electroshock (ES) in our clinic, in addition to the therapeutic results, has also provided an opportunity to further investigate the basic and concomitant phenomena of the spasm mechanism. In this brief, quasi-preliminary report, we describe the ocular fundus lesions associated with spasm. As the essence of shock therapy is seen by many authors (Abély, Delay, Morin, Gastant, Cain) in the stimulation of the diencephalon, and Krienberg and Eberhardt have drawn attention to the fundamental importance of cerebral blood circulation in the mechanism of shock, the study of the orbital vessels of the fundus is of prime importance. The behaviour of the fundus blood vessels provides an analogous picture of the probable identical behaviour of the cerebral blood vessels, and the vasovegetatively congruent state of the pupils and fundus blood vessels also provides information on the fluctuations of the vegetative tone.]

Clinical Neuroscience

JULY 29, 1952

[Foreign Language Summaries]

[A summary of the articles published in the issue in Russian and German]