Lege Artis Medicinae

[Cardiovascular risk factors associated with albuminuria in insulin-dependent diabetic patients]

JERMENDY György1, VÖRÖS Péter2, STOKUM Éva3, KAMMERER László2

SEPTEMBER 25, 1991

Lege Artis Medicinae - 1991;1(15)

[The appearance of albuminuria could be associated with increased risk of cardiovascular morbidity and mortality in insulin-dependent diabetic patients. For assessing this relationship 81 insulin-dependent diabetic patients were investigated. Albuminuria was detected by radioimmunoassay and diabetics were classified as having normo, micro- or macroalbuminuria. In macroalbuminuric patients (n = 16) serum creatinine, total cholesterol, triglycerides, uric acid and blood pressure were significantly higher than in normoalbuminuric patients (n = 45). Values of microal buminuric patients (n = 20) were between those of macro- and normoalbuminuric diabetics. Close correlations were found bet ween albumin excretion rate and serum creatinine, cholesterol, triglycerides, uric acid, systolic and diastolic blood pressure. Cardiovascular risk factors are increasingly present in insulin-dependent, non-uraemic diabetic patients with albuminuria playing a possible role in the excess rate of cardiovascular morbidity and mortality. ]

AFFILIATIONS

  1. főorovs Fővárosi István Kórház Merényi Gusztáv Kórháza Belgyógyászati Osztály
  2. főorvos Fővárosi István Kórház II. Belgyógyászati Osztály
  3. vegyészmérnök Chinoin Rt. Biokémiai Kutató Laboratórium Budapest

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