Lege Artis Medicinae

[CALM]

MATOS Lajos

MAY 20, 2004

Lege Artis Medicinae - 2004;14(05)

COMMENTS

0 comments

Further articles in this publication

Lege Artis Medicinae

[16th National Conference of the Supervisors of General Practitioners]

KRAMER Imre

Lege Artis Medicinae

[9th Debrecen Cardiology Days]

PÁLVÖLGYI Nóra, MOHÁCSI Attila

Lege Artis Medicinae

[NEUROFIBROMATOSIS, MALIGNANT MELANOMA AND HYPERTHYREOIDISM IN A HCV POSITIVE PATIENT]

FOLHOFFER Anikó, HORVÁTH Andrea, CSÁK Tímea, NÉBENFÜHRER László, TELKES Márta, IVÁNYI András, SZALAY Ferenc

[INTRODUCTION - Similar occirrence of neurofibromatosis and malignant melanoma is rare. We report a patient with neurofibromatosis, cutaneous melanoma, hyperthyreoidism and HCV positivity. CASE REPORT - A 43-year-old woman has been under care for neurofibromatosis for 16 years when she presented with increased serum ?- glutamyltransferase, alkaline phosphatase activity and anti-HCV antibody positivity at regular checkup. A pigmented lesion removed from her back histologically proved to be cutan melanoma. Interferon treatment was applied. She lost 8 kilograms in half a year which was caused not by the tumor progression, but hyperthyreoidism. A rapid clinical and laboratory improvement was observed for thyreostatic treatment and she regained her bodyweight. One year later she presented with a cough caused by pulmonary tumor. The tumor was surgically removed and histologically diagnosed as metastasis of melanoma. Cytostatic treatment was applied and she became asymptomatic. Four years after the diagnosis of melanoma she died of apoplexy. During the autopsy there was no sign of either melanoma or liver disease. CONCLUSIONS - The careful investigation of skin should be emphasised even in case of long established neurofibromatosis. The presented case shows an association of malignant melanoma and neurofibromatosis. In the background of loss of bodyweight even in a patient with history of malignant disease other causes should also be searched such as hyperthyreoidism especially during interferon therapy.]

Lege Artis Medicinae

[CURRENT STATUS OF THE DIAGNOSTICS AND THERAPY OF UROLOGICAL TUMOURS]

ROMICS Imre

[Significant amount of urological patients have malignant disease. Prostate cancer is the second most frequent cancer in males associated with high mortality and decreased quality of life. Hence the importance of early diagnosis. Furthermore, diagnostical protocols, operative and conservative therapeutic modalities are summarised. Hematuria is the most frequent sign of bladder cancer. Diagnostical, surgical and adjuvant therapeutical differencies of the superficial and muscle invasive bladder cancers are discussed. The urinary deviation after cystectomy could be associated with complications therefore regular follow up of patients is necessary. The standard therapy of renal cancer is surgical. Unfortunately its mortality has not change during past years. Testicular cancer is the disease of young males. If diagnosed early, most cases are curable. Therapy is complex, involving surgical, chemoand radiation therapy as well. Penis cancer is a rare disease, but highly malignant. In advanced stage patients are incurable.]

Lege Artis Medicinae

[IDENTIFYING HELICOBACTER PYLORI WITH DNA-BASED ASSAYS]

RUZSOVICS Ágnes, MOLNÁR Béla, TULASSAY Zsolt

[The DNA-based assays have the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA. Markers used include general H. pylori structures and pathogenetic factors like ureaseA, cagA, vacA, iceA. DNA or bacterial RNA for polymerase chain reaction (PCR) assays can be collected from gastric biopsy, gastric juice, stool, buccal specimens. PCR can yield quantitative and genotyping results with sensitivity and specificity that approaches 100%. A clear trend in the direction of the determination of quantitative H. pylori infection by real-time PCR can be observed. Fluorescent in situ hybridisation (FISH) and restriction fragment length polymorphism (RFLP) are suggested for routine antibiotic resistance determination. To identify the DNA structure of organism and its virulence factors may be feasible by using oligonucleotide microarray specifically recognising and discriminating bacterial DNA and various virulence factors. DNA based H. pylori diagnosis yields higher sensitivity, however, specificity requires sophisticated labour environment and associated with higher costs.]

All articles in the issue

Related contents

Lege Artis Medicinae

[Oxytocin as a neurotransmitter: beyond the peripheral scope]

VARGA Katalin

[Besides its effect on the uterus and breasts, oxytocin also regulates affiliative behaviour. The so-called central oxytocin effect influences pair bonding, maternal care and attachment through the regulatory functions of oxytocin that acts as a neurotransmitter within the brain. The central oxytocin effect increases trust and social support, decreases fear and anxiety, and promotes wound healing. These effects form the basis of the stress-triggered, oxytocin-based ‘calm and connection’ reaction. Some methods that are widely used in modern obstretric practice - such as the use of synthetic oxytocin for inducing or speeding up labour or epidural anaesthesia - hinder the psycho-emotive effects that are based on natural oxytocin. Epigenetic studies performed in animals indicate that the oxytocin effect experienced at birth can be transgenerational.]

Journal of Nursing Theory and Practice

[Investigation of nurses eating habits]

NÉMETH Anikó

[The aim of the study: was to assess the characteristics of diet among nurses in relation to socio-demographic and workplace related factors. Methods: The survey was conducted in 2015 through a self-constructed online questionnaire. Data were analyzed with SPSS 22.0 using chi square, Mann-Whitney and Kruskal-Wallis tests. Results: Sixty percent of the 548 involved nurses are overweight. Monthly overtime correlates negatively with the number of daily meals (p=0.003) with having hot meals (p=0.022) and with the opinion about dietary habits (p=0.001). Calm meals are typical for 30%, eating vegetables, fruits and whole grain bakery products for 20% and only 24.3% drinks two litres per day. Having children has beneficial effects on dietary habits. Conclusions: It can be concluded that the majority of the nurses included are overweight and they have dissatisfactory diet. The reasons for these might be rooted in the characteristics of the job and the Hungarian eating habits.]