Lege Artis Medicinae

[Blood pressure variability and its clinical importance]

KÉKES Ede1, VÁLYI Péter 2,3

MAY 26, 2022

Lege Artis Medicinae - 2022;32(04-05)

DOI: https://doi.org/10.33616/lam.32.014


[The 24-hour and longer-term (weeks, months, years) as well as seasonal, regional variations and fluctuations of blood pressure have been known for long time in both normotensive and hypertensive patients. It is also well known and established that blood pressure variability is greater in patients with more severe hypertension and in the elderly population. In the last decade and actually, the variability of blood pressure has come into new light by meticulous analysis of numerous causal factors and consequences influencing its fluctuation. The real diagnostic and prognostic value of blood pressure variability and its role in the assessment of successful antihypertensive treatment have also been favoured. In our review, we summarise the physiological and pathophysiological principles of blood pressure variability, including also the significant importance of allostasis in the new approach. We overview the methods of measuring the blood pressure variability and its real importance related to the results obtained. We analyse the importance of non-adaptive levels of blood pressure variability in asymptomatic cases and apparent conditions, further in diagnostic projections and monitoring the treatment. Based on our own experience, we also present the future options of exploring the fluctuating blood pressure.]


  1. Pécsi Tudományegyetem, Klinikai Központ, Kardiológiai Tanszék
  2. Érgondnok Rendelőház, Sopron
  3. VALYTERAPIA Egészségügyi és Szolgáltató Bt., Győr



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