Hypertension and nephrology

[Pyelonephritis acuta]

APRIL 29, 2021

Hypertension and nephrology - 2021;25(2)

[Primarily bacterial infections (E. coli, Proteus mirabilis, Klebsiella, Enterococcus), tubules, interstitium, acute inflammatory condition of the renal calves and pelvic pelvis. Most often as a result of ascending urinary tract infection less frequently due to haematogenic variance. Risk factors for the development of diabetes are immunosuppressive condition, obstructive in maintaining urinary retention uropathies (kidney stones, tumors, or congenital urotra or acquired dysfunction and / or anatomical abnormalities), and instrumental interventions on the urinary tract and pregnancy.]

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Hypertension and nephrology

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[In spite of the diverse etiology, chronic kidney disease is finally leading to end-stage renal disease uniformly by the fibrotic transformation of the kidneys. In recent years – mainly due to experimental data – the explanation of this transformation changed profoundly: it has been revealed, that renal fibrosis is a dynamic, actively ongoing process involving many keyfactors. Influencing these factors, give us hope to prevent the progression of chronic kidney disease. This review summarizes the connection of renal fibrosis and chronic kidney disease, the results of the widely used different methods and the recently discovered mechanisms, which caused paradigm change in this topic]

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