Hypertension and nephrology

[Primary aldosteronism, the mysterious object of desire – in the context of a study]

BAJNOK László1

APRIL 29, 2021

Hypertension and nephrology - 2021;25(2)

DOI: https://doi.org/10.33668/hn.25.008

[The aldosterone-producing adenoma, aldosteronoma, the actual Conn syndrome, is a relatively well-defined entity, while the separability of idiopathic hyperaldosteronism and low-renin primary hypertension appears to be inherently uncertain according to our current knowledge. In this way, the diagnosis of primary aldosteronism (PA) is in fact more or less probabilistic and this also contributes fundamentally to the uncertainty of prevalence data. These are confirmed by a recent study in which PA was evaluated in the form of 24- hour urinary aldosterone excretion measured with oral salt loading instead of the standard technique. The paper has contributed to the change of paradigm by which the chair of the most widely accepted PA guideline, renewed in 2016, called to be jettisoned much of it.]


  1. Pécsi Tudományegyetem, I. Sz. Belgyógyászati Klinika, Endokrinológiai és Anyagcsere Tanszék, Pécs



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