Hypertension and nephrology

[Bottlenecks in primary aldosteronism care – focus on screening and biochemical diagnosis]

BAJNOK László1

JULY 05, 2022

Hypertension and nephrology - 2022;26(03)

DOI: https://doi.org/10.33668/hn.26.017

[ The primary (hyper) aldosteronism (PA) is a spectral disease forming a continuum from normotensive to cases that warrant adrenalectomy. PA definition is laden with inherent uncertainties. The main paradigm shift in the two new recommendations described below is that no change in medication is recommended before PA screening, to help broaden the scope of screenings. Both continue to be based on suppressed renin activity, but the serum aldosterone threshold has been lowered to increase sensitivity. With this algorithm, however, the proportion of positive screenings is significantly increased, creating another bottleneck, leading to congestion of patients referred to a specialist to perform an additional suppression test.]


  1. Pécsi Tudományegyetem, I. Sz. Belgyógyászati Klinika, Endokrinológiai és Anyagcsere Tanszék



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