Clinical Neuroscience

[Diffuse cortical necrosis following pertussis]

CSERMELY Hubert1, FÁBER Viktor1

SEPTEMBER 01, 1959

Clinical Neuroscience - 1959;12(09)

[The neurological complications of pertussis are relatively rare but significant, with a third being fatal and, in some cases, permanent damage if survival is not achieved. (1) haemorrhage into the subdural or subarachnoid space and massive interacerebral haemorrhage, or white matter ring and globe haemorrhages, (2) cellular degenerations caused by anoxia-vascular damage, this is the true pertussis encephalopathy. 3. parainfectious encephalitis. The latter is the rarest, with only one authentic case known to date (Möller). Clinical detection of pertussis encephalopathy is more common, but pathological confirmation is rare. ]

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  1. Gyöngyösi Városi Tanács Bugát Pál Kórháza és a Magyar Néphadsereg eü. szolgálata

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[Anoxic brain findings in status epilepticus associated with acute alcohol intoxication]

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[13-year-old boy died of acute alcohol poisoning 30-32 hours after poisoning. Clinical features were circulatory failure, decerebration and serial epileptic seizures. At autopsy, the brain was oedematous. Histopathologically, laminar necrosis was found extending over almost the entire cerebral cortex (except the area striata). Not only the cells of layers III and V were degenerated (mainly ischemic cell changes), but also the granule cells (shrinkage). The mesenchymal reaction was marked, but gliosis and marrow sheathing were not yet present, which testifies to the acute nature of the lesions. Cortical necrosis is considered to be a consequence of alcohol-induced status epilepticus.]

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[1. The reflexes of "spinal automatism", namely the crossed extensor reflex, can only be triggered in normal preterm and mature newborns exceptionally, but not regularly, when tested with the techniques used so far. 2. Using a technique hitherto used only in animal experiments, the crossed extensor reflex can be elicited normally at very low stages of development of the nervous system. 3. The crossed inguinal extensor reflex, a variant of the crossed extensor reflex, decreases in intensity during ontogenetic development: it first appears in rudimentary forms and then gradually disappears and becomes clinically latent or clinically inactive during the first year of life. 4. EMG studies have shown that the crossed inguinal extensor reflex and the flexor reflex activate not only the muscles involved in the named reflexes but also their antagonists. 5. Thus, with the application of appropriate methodology, flexion and extensor reflexes can be elicited simultaneously at early stages of nervous system development. The phenomenon itself could be called co-reflex.]

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[Symposium on current encephalitis]

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[Symposium on current encephalitis with 60-65 experts from 14-15 countries Symposium (S) was held at the Institut de Médicine Tropicale in Antwerp, Belgium, at the initiative of the Belgian Centre Interuniversitaire de Recherche Neuropathologiques, with the support of the World Federation of Neurology and the US National Institute of Neurology and Blindness. Ludo van Bogáért was the conceptual founder, organiser and president of the S.]

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