Lege Artis Medicinae - 2005;15(02 klsz)

Lege Artis Medicinae

NOVEMBER 30, 2004

[CLINICAL PROFILE, EFFICACY AND SAFETY OF LONG-ACTING INJECTABLE RISPERIDONE]

BÁNKI M. Csaba

[Schizophrenia is a severe and chronic disorder affecting almost 1% of the population worldwide. Antipsychotic drugs, currently in their secondgeneration (atypical) antipsychotics, represent its first-line treatment. Compliance during long-term maintenance pharmacotherapy is one of the key factors in successful patient management; longacting, injectable antipsychotics may significantly contribute to the improvement of the patients The new form of this drug is the first long-acting, injectable... tovább »

Lege Artis Medicinae

NOVEMBER 30, 2004

[SUCCESSFUL TREATMENT WITH LONG-ACTING INJECTABLE RISPERIDONE]

TÉNYI Tamás

[INTRODUCTION - In the past 15 years new antipsychotic drugs have come forward with higher efficacy in the treatment of schizophrenia. These new medications are safer and have less side-effects. It is now established that longacting maintenance therapy is favourable than intermittent therapy CASE PRESENTATION - The author introduces the case of a male schizophrenic patient who was hospitalized three times over ten years. He discontinued maintenance therapy because of lack of symptoms first... tovább »

Lege Artis Medicinae

NOVEMBER 30, 2004

[ANTIPSYCHOTIC DRUGS - A SHORT HISTORY]

BITTER István

[The first drug used as an antipsychotic was chlorpromazine in 1952. The effective drugs after chlorpromazine in the treatment of schizophrenia and acute manic episodes were named as “major tranquillants” then neuroleptic drugs and later as first-generation antipsychotics. The discovery of clozapin has opened a new era in psychiatric therapy which was followed by new antipsychotics with less and less neurological sideeffects. These are called atypical neuroleptics or second generation... tovább »

Lege Artis Medicinae

NOVEMBER 30, 2004

[PROBLEMS WITH THE COMPLIANCE OF SCHIZOPHRENIC PATIENTS - CAUSES, CONSEQUENCES AND STRATEGIES FOR ITS MANAGEMENT]

BARTKÓ György

[As many as 80% of patients with schizophrenia have serious problems with the compliance at some point during their course of their treatment. In most cases, patients are partially compliant, taking only a portion of their prescribed medication. Early warning signs of such partial compliance may confuse some clinicians with non-response to treatment and may result in switching these patients to alternative oral antipsychotic drugs. This review focuses on factors that can contribute to partial... tovább »