Lege Artis Medicinae

[Clinical and immunological aspects of polymyositis and dermatomyositis]

DANKÓ Katalin1, ZILAHI Zsolt1, SZEGEDI Gyula1

SEPTEMBER 30, 1992

Lege Artis Medicinae - 1992;2(09)

[Polymyositis and dermatomyositis are autoimmune diseases characterized by muscle weakness, tenderness, occasionally pain, and ultimately atrophy and fibrosis of the muscles. The extraskeletal manifestations, particularly the cardiopulmonary, oropharyngeal, gastrointestinal involvement, are described. Studies of autoantibodies and cellular immune function support a central role for disordered immunity in the pathogenesis. The myositis-specific autoantibodies, expecially those directed at certain enzymes important in protein synthesis are found in a clinically distinct subset of patients. ]

AFFILIATIONS

  1. Debreceni Orvostudományi Egyetem III. sz. Belgyógyászati Klinika

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