Hungarian Immunology - 2002;1(02)

Hungarian Immunology

JUNE 20, 2002

[Anti-synthatase syndrome]

PONYI Andrea, CONSTANTIN Tamás, DANKÓ Katalin

[The idiopathic inflammatory myopathies (IIM) are autoimmune diseases, characterized by symmetric proximal muscle weakness. Over the last several decades, many abnormalities of the cellular and humaral immune systems of IIM patients have been described. Some of these are autoantibodies unique to the IIM (the myositis specific autoantibodies MSA). The MSAs are antigen-driven, arise months prior to the onset of myositis, correlate in titre with disease-activity. Studies in the recent years proved... tovább »

Hungarian Immunology

JUNE 20, 2002

[Autoimmun thyroiditis presence in patient with Hodgkin’s disease in remission]

BÍRÓ Edit, BAKÓ Gyula, SZEGEDI Gyula, ILLÉS Árpád

[INTRODUCTION - It is known that the incidence of hypothyroidism is higher in long term survivor patients with Hodgkin's disease, and it is supposed to be the result of treatment, such as neck radiotherapy. The author believe that other etiologic factors may also play a role in the development of hypothyroidism. PATIENTS AND METHODS - Looking for the possible causes of hypothyroidism, the thyroid function of 151 patients treated for Hodgkin's disease since 1970 were examined. These patients... tovább »

Hungarian Immunology

JUNE 20, 2002

[Ocular myositis]

KISS Emese, FACSKÓ Andrea, DÉVÉNYI Katalin, DANKÓ Katalin, ZEHER Margit

[INTRODUCTION - Dermato-/polymyositis is an autoimmune disorder, which belongs to the idiopathic inflammatory myopaties. It involves skeletal muscles in form of weakness and inflammatory infiltrates. Characteristic skin lesions are present in dermatomyositis. Other organs may also be affected mainly in the presence of myositis specific autoantibodies. The inflammation usually involves the proximal muscles of extremities. CASE REPORT - In the present work we report the case of a 52-year-old... tovább »

Hungarian Immunology

JUNE 20, 2002

[Changes in the signal transduction of T-lymphocytes caused by hyperglycemia]

BOLDIZSÁR Ferenc, BERKI Tímea, MISETA Attila, NÉMETH Péter

[AIMS - Lately the altered calcium balance of different cell types (eg.: erythrocytes, platelets, neutrophil granulocytes) was described in diabetes mellitus. It is also known that patients with diabetes mellitus suffer from various infections more often then healthy individuals because of immunological malfunctions. But the mechanism of these changes is still unclear. In order to investigate the effect of hyperglycemia on the function of immunocompetent cells we established an in vitro... tovább »