Clinical Neuroscience

[Transaminase in cerebrospinal fluid ]

LÁNG Sándor1

JULY 01, 1968

Clinical Neuroscience - 1968;21(07)

[The CSF cerebrospinal fluid glutamic acid oxaloacetic acid transaminase (GOT) level is normally low, 5-30 units. There is no significant difference between cisternal and lumbar CSF. In old age (over 50 years), transaminase levels may also rise above normal in healthy subjects. GOT is not elevated in epilepsy (except status epilepticus), multiple sclerosis, polyneuritis, polyradiculitis - No change in meningitis of various origins except for 1 or 1 spike. Normal values in benign CNS tumours and higher values in extensive malignancies. In vascular disease (atherosclerosis, stroke, cerebral thrombosis), CSF transaminase levels are increased in one third to one half of cases. Elevated CSF GOT is not specific to a single disease and should only be evaluated in conjunction with clinical signs and other laboratory tests.]

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  1. BOTE Psychiatriai Klinika

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