Clinical Neuroscience

[Intracranial respiratory epithelial cysts: report of two cases]

VARGA Zs1, VAJTAI I1, BODOSI M2, VÖRÖS E3

MARCH 20, 1996

Clinical Neuroscience - 1996;49(03-04)

[The authors report two cases of leptomeningeal cysts with unusual histologic features. Both cysts originated in the subarachnoid space of the left Sylvian fissure, being solitary in one case and multiocular in the other. Symptoms in both cases were referable to intracranial space occupation. Both lesions were resected surgically. Microscopically, the cyst walls were predominantly lined with pseudostratified and ciliated columnar or non-keratinizing squamous epithelium reminiscent of various segments of the respiratory mucosa. Ependymal covering was present only focally. The cellular elements displayed a characteristic immunophenotype and there was evidence for mucin production. Intracranial respiratory epithelial cysts are distinctly rare. While a dysontogenic origin is presumed for such cysts are distinctly rare. While a dysontogenic origin is persumed for such cysts along the spinal cord, intracranial occurrences are most plausibly interpreted as a result of metaplastic transformation of the meningeal anlage induced by cyst expansion. ]

AFFILIATIONS

  1. Szent-Györgyi Albert University Medical School, Department of Pathology
  2. Department of Neurosurgery
  3. Department of Radiology, Szeged

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