Lege Artis Medicinae

[Metabolic syndrome - metabolic risk factors]

AUDIKOVSZKY Mária1, PADOS Gyula1

OCTOBER 01, 2000

Lege Artis Medicinae - 2000;10(10)

[Since abdominal type obesity, diabetes mellitus and the metabolic syndrome were classified as primary coronary risk factors beside hypercholesterolaemia and smoking, five out of six of the most significant risk factors are regarded of metabolic origin. Simultaneous occurrence of these factors are far more frequent in the population. The composition and background of this syndrome were subject of numerous analyses and classification from syndrome-X to metabolic syndrome. Reaven finds insulin resistance and compensatory hyperinsulinism as the primary cause, while Matsuzava et al regards visceral type obesity (visceral fat syndrome), and Björntrop views the increase in sympathetic tone (civilization syndrome) as fundamental. In the diagnostics and therapy of the metabolic syndrome we should consider all factors mentioned above. We have to establish the presence of three or more classic risk factors for a firm diagnosis. In the therapy, decreasing the body weight with diet and exercise is crucial, with adjuvant drug therapy of antidiabetics, insulinsensitizers, lipid lowering agents and antihypertensives, as needed. ]

AFFILIATIONS

  1. Szent Imre Kórház, IV. Belgyógyászat, Budapest

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